Manuchehri Kaykhosrov, Kirkby Graham
Birmingham and Midland Eye Centre, City Hospital, Birmingham, UK.
Drugs Aging. 2003;20(9):655-61. doi: 10.2165/00002512-200320090-00003.
Vitreous haemorrhage can be caused by a disruption of normal retinal vessels, bleeding from diseased retinal vessels, bleeding from abnormal new vessels or extension of haemorrhage through the retina from other sources. In the elderly, vitreous haemorrhage usually occurs spontaneously and only occurs occasionally as a result of trauma. Appropriate management of vitreous haemorrhage is dependent on the most likely cause in a particular patient. As always, an accurate medical history with a careful clinical examination, static and dynamic ultrasonography performed by an experienced examiner, results of other laboratory tests and an understanding of the common causes of vitreous haemorrhage in each age group is essential to come to a 'best guess' diagnosis as to the cause of the vitreous haemorrhage and thus guide the physician toward the appropriate management. Immediate surgical removal of blood if indicated, as well as improving the vision gives the added benefit of allowing a full examination of the underlying retina. For those in whom surgical removal of blood is not recommended, a careful and frequent follow-up with serial B-scan ultrasound allows the 'best guess' diagnosis to be confirmed at each visit, until such time as the vitreous haemorrhage resolves sufficiently to allow a full and proper examination of the retina. Where there is a confirmed retinal tear, retinal detachment or other fundal pathology these are treated appropriately with laser or surgery (vitrectomy). Preventative measures are dependent on the underlying cause of vitreous haemorrhage. Some of the underlying causes such as posterior vitreous detachment cannot be prevented. In others, such as retinal vein occlusion, measures may need to be taken so as to reduce the risk of a similar event in the same or fellow eye and to reduce the risk of potentially life-threatening associated systemic conditions such as a stroke or myocardial infarction.
玻璃体积血可由正常视网膜血管破裂、病变视网膜血管出血、异常新生血管出血或出血从其他来源经视网膜扩展至玻璃体引起。在老年人中,玻璃体积血通常自发发生,仅偶尔因外伤导致。玻璃体积血的恰当处理取决于特定患者最可能的病因。一如既往,准确的病史、仔细的临床检查、由经验丰富的检查者进行的静态和动态超声检查、其他实验室检查结果以及对各年龄组玻璃体积血常见病因的了解,对于“最佳猜测”玻璃体积血的病因诊断至关重要,从而指导医生进行恰当处理。如有指征,立即手术清除血液以及改善视力还有额外益处,即能对潜在的视网膜进行全面检查。对于不建议手术清除血液的患者,通过连续B超超声进行仔细且频繁的随访,可在每次就诊时确认“最佳猜测”诊断,直至玻璃体积血充分吸收,能够对视网膜进行全面且恰当的检查。若确诊存在视网膜裂孔、视网膜脱离或其他眼底病变,则用激光或手术(玻璃体切除术)进行适当治疗。预防措施取决于玻璃体积血的潜在病因。有些潜在病因,如玻璃体后脱离,无法预防。在其他情况下,如视网膜静脉阻塞,可能需要采取措施以降低同一眼或对侧眼发生类似事件的风险,并降低诸如中风或心肌梗死等潜在危及生命的相关全身性疾病的风险。