[抑肽酶对神经缝合处纤维化的影响]
[Effect of aprotinin on fibrosis of nerve sutures].
作者信息
Herter T, Windmann D
机构信息
Klinik und Poliklinik für Neurochirurgie, Westfälischen Wilhelms-Universität Münster.
出版信息
Handchir Mikrochir Plast Chir. 1992 Nov;24(6):315-8.
Although fibrin-glue has been used in many areas of surgery, it has not become fully established in nerve coaptation. Initially, significant advantages were expected; however, as the fibrin clot dissolved prematurely and gapping occurred, antifibrinolytic substances were added to the glue. Following this procedure, fibroses occurred frequently, which remains a problem. In this study, the influence of aprotinin's fibrosis-inducing effect was investigated. Aprotinin demonstrated no additional fibrosis-promoting effect.
尽管纤维蛋白胶已在许多外科领域得到应用，但在神经吻合术中尚未完全确立其地位。最初，人们预期它会有显著优势；然而，由于纤维蛋白凝块过早溶解并出现间隙，于是在胶中添加了抗纤溶物质。采用此方法后，纤维化频繁发生，这仍是一个问题。在本研究中，对抑肽酶的纤维化诱导作用的影响进行了调查。抑肽酶未显示出额外的促进纤维化作用。
Zotero 插件