Böhner Hinrich, Hummel Thomas C, Habel Ute, Miller Caesar, Reinbott Stefan, Yang Qin, Gabriel Andrea, Friedrichs Ralf, Müller Eckhard E, Ohmann Christian, Sandmann Wilhelm, Schneider Frank
Department of Vascular Surgery and Kidney Transplantation, School of Medicine, Heinrich-Heine Universität, Düsseldorf, Germany.
Ann Surg. 2003 Jul;238(1):149-56. doi: 10.1097/01.sla.0000077920.38307.5f.
The aim of the study was to determine pre- and intraoperative risk factors for the development of postoperative delirium among patients undergoing aortic, carotid, and peripheral vascular surgery to predict the risk for postoperative delirium.
Although postoperative delirium after vascular surgery is a frequent complication and is associated with the need for more inpatient hospital care and longer length of hospital stay, little is known about risk factors for delirium in patients undergoing vascular surgery.
Pre-, intra-, and postoperative data were prospectively collected, including the first 7 postoperative days with daily follow-up by a surgeon and a psychiatrist of 153 patients undergoing elective vascular surgery. Delirium (Diagnostic and statistical Manual of Mental Disorders IV) was diagnosed by the psychiatrist. Multivariate linear logistic regression and a cross validation analysis were performed to find a set of parameters to predict postoperative delirium.
Sixty patients (39.2%) developed postoperative delirium. The best set of predictors included the absence of supraaortic occlusive disease and hypercholesterinemia, history of a major amputation, age over 65 years, a body size of less than 170 cm, preoperative psychiatric parameters and intraoperative parameters correlated to increased blood loss. The combination of these parameters allows the estimation of an individual patients' risk for postoperative delirium already at the end of vascular surgery with an overall accuracy of 69.9%.
Postoperative delirium after vascular surgery is a frequent complication. A model based on pre- and intraoperative somatic and psychiatric risk factors allows prediction of the patient's risk for developing postoperative delirium.
本研究旨在确定接受主动脉、颈动脉和外周血管手术患者术后谵妄发生的术前和术中危险因素,以预测术后谵妄的风险。
尽管血管手术后的术后谵妄是一种常见并发症,且与更多住院护理需求和更长住院时间相关,但对于接受血管手术患者谵妄的危险因素知之甚少。
前瞻性收集术前、术中和术后数据,包括153例接受择期血管手术患者术后的前7天,由外科医生和精神科医生进行每日随访。精神科医生诊断谵妄(《精神疾病诊断与统计手册》第四版)。进行多变量线性逻辑回归和交叉验证分析,以找到一组预测术后谵妄的参数。
60例患者(39.2%)发生术后谵妄。最佳预测指标包括无主动脉弓上闭塞性疾病和高胆固醇血症、大截肢病史、年龄超过65岁、身高小于170 cm、术前精神参数以及与失血增加相关的术中参数。这些参数的组合能够在血管手术结束时就估计个体患者术后谵妄的风险,总体准确率为69.9%。
血管手术后的术后谵妄是一种常见并发症。基于术前和术中躯体及精神危险因素的模型能够预测患者发生术后谵妄的风险。