Marcoval Joaquim, Moreno Abelardo, Mañá Juan
Department of Dermatology, Pathology, Hospital de Bellvitge, University of Barcelona, Spain.
J Am Acad Dermatol. 2003 Jul;49(1):75-8. doi: 10.1067/mjd.2003.490.
In recent years we have systematically explored the skin whenever sarcoidosis was suggested and we have observed with increasing frequency the presence of granulomatous cutaneous lesions of sarcoidosis involving the knees.
We sought to evaluate the specific cutaneous lesions of sarcoidosis involving the knees.
A total of 18 patients with biopsy-proven specific cutaneous sarcoidosis predominantly involving the knees were included in the study. Biopsy specimens were evaluated under polarized light.
Of these cases, 4 corresponded to scar-sarcoidosis, 1 to plaque-type sarcoidosis, and 13 were an admixture of papules and minute scars frequently associated with erythema nodosum (papular sarcoidosis of the knees). Foreign particles were observed in 10 of 13 patients with papular sarcoidosis.
Papular sarcoidosis of the knees can be considered a frequent form of cutaneous sarcoidosis, mainly observed in acute forms of the disease, and frequently associated with erythema nodosum.
近年来,每当怀疑有结节病时,我们都会对皮肤进行系统检查,并且越来越频繁地观察到结节病的肉芽肿性皮肤病变累及膝盖。
我们试图评估结节病累及膝盖的特异性皮肤病变。
本研究共纳入18例经活检证实的主要累及膝盖的特异性皮肤结节病患者。活检标本在偏振光下进行评估。
在这些病例中,4例为瘢痕结节病,1例为斑块型结节病,13例为丘疹与微小瘢痕的混合,常伴有结节性红斑(膝盖丘疹性结节病)。在13例丘疹性结节病患者中的10例观察到异物颗粒。
膝盖丘疹性结节病可被认为是皮肤结节病的一种常见形式,主要见于疾病的急性形式,且常与结节性红斑相关。