胃纤维黄色瘤中的克隆性细胞遗传学异常及端粒关联

Clonal cytogenetic abnormalities and telomeric associations in a fibroxanthoma of the stomach.

作者信息

Seruca R, Carneiro F, Soares P, Fonseca E, Castedo S

机构信息

Department of Pathology, Medical Faculty of Porto, Portugal.

出版信息

Genes Chromosomes Cancer. 1992 Nov;5(4):407-9. doi: 10.1002/gcc.2870050418.

DOI:10.1002/gcc.2870050418

PMID:1283331

Abstract

A cytogenetic study of a fibroxanthoma (fibrous histiocytoma) of the stomach revealed a clonal structural abnormality involving chromosome 12 and frequent telomeric associations between the short arm of chromosome 12 and different chromosomes. A marker chromosome possibly derived from chromosome 11 was also present. This is the second reported case of gastric fibroxanthoma and the first studied cytogenetically.

摘要

一项对胃纤维黄色瘤（纤维组织细胞瘤）的细胞遗传学研究显示，存在涉及12号染色体的克隆性结构异常，且12号染色体短臂与不同染色体之间频繁出现端粒关联。还存在一条可能源自11号染色体的标记染色体。这是第二例报道的胃纤维黄色瘤病例，也是首例进行细胞遗传学研究的病例。