纳曲酮使用不当对海洛因滥用者的影响。
Effect of innappropriate naltrexone use in a heroin misuser.
作者信息
Boyce S H, Armstrong P A R, Stevenson J
机构信息
Accident and Emergency Department, Crosshouse Hospital, Kilmarnock, UK.
出版信息
Emerg Med J. 2003 Jul;20(4):381-2. doi: 10.1136/emj.20.4.381.
Abstract
Naltrexone is a long acting opioid receptor antagonist used in controlled opioid withdrawal drug programmes. When taken by an opioid dependent patient an acute withdrawal reaction will be precipitated. The case is presented where a known opioid drug misuser inadvertently ingested naltrexone in conjunction with heroin resulting in severe agitation, requiring heavy sedation followed by general anaesthesia to enable investigation and management of his clinical condition.
摘要
纳曲酮是一种长效阿片受体拮抗剂，用于可控的阿片类药物戒断治疗项目。阿片类药物依赖患者服用后会引发急性戒断反应。本文介绍了一例已知的阿片类药物滥用者意外将纳曲酮与海洛因一起摄入，导致严重躁动，需要深度镇静，随后进行全身麻醉以便对其临床状况进行检查和处理的病例。
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