丁丙诺啡治疗口服纳曲酮诱导的阿片类药物戒断：病例报告。
Buprenorphine therapy in the setting of induced opioid withdrawal from oral naltrexone: a case report.
机构信息
Department of Pharmacology, Upstate Medical University, 750 E Adams St, Syracuse, NY, 13210, USA.
Department of Emergency Medicine, Upstate Medical University, 750 E Adams St, Syracuse, NY, 13210, USA.
出版信息
Harm Reduct J. 2020 Oct 7;17(1):71. doi: 10.1186/s12954-020-00417-9.
BACKGROUND
Patients with opioid use disorder (OUD) frequently present to the emergency department for acute treatment of overdose and withdrawal.
CASE PRESENTATION
A 29-year-old male presented to the emergency room after intravenous heroin use followed by accidental ingestion of naltrexone. He was treated with buprenorphine with significant improvement in his Clinical Opioid Withdrawal Score, from moderately severe to mild withdrawal symptoms within a few hours.
CONCLUSION
Buprenorphine and minimal supportive care can be used to treat acute withdrawal precipitated by oral naltrexone in patients with OUD.
背景
患有阿片类药物使用障碍（OUD）的患者经常因急性药物过量和戒断症状到急诊室接受治疗。
病例介绍
一名 29 岁男性在静脉注射海洛因后意外摄入纳曲酮，随后到急诊室就诊。他接受了丁丙诺啡治疗，其临床阿片类戒断评分在数小时内从中度到轻度戒断症状显著改善。
结论
在 OUD 患者中，可使用丁丙诺啡和最小的支持性护理来治疗由口服纳曲酮引发的急性戒断。
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