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丁丙诺啡治疗口服纳曲酮诱导的阿片类药物戒断：病例报告。

Buprenorphine therapy in the setting of induced opioid withdrawal from oral naltrexone: a case report.

机构信息

Department of Pharmacology, Upstate Medical University, 750 E Adams St, Syracuse, NY, 13210, USA.

Department of Emergency Medicine, Upstate Medical University, 750 E Adams St, Syracuse, NY, 13210, USA.

出版信息

Harm Reduct J. 2020 Oct 7;17(1):71. doi: 10.1186/s12954-020-00417-9.

DOI:10.1186/s12954-020-00417-9
PMID:33028340
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7542394/
Abstract

BACKGROUND

Patients with opioid use disorder (OUD) frequently present to the emergency department for acute treatment of overdose and withdrawal.

CASE PRESENTATION

A 29-year-old male presented to the emergency room after intravenous heroin use followed by accidental ingestion of naltrexone. He was treated with buprenorphine with significant improvement in his Clinical Opioid Withdrawal Score, from moderately severe to mild withdrawal symptoms within a few hours.

CONCLUSION

Buprenorphine and minimal supportive care can be used to treat acute withdrawal precipitated by oral naltrexone in patients with OUD.

摘要

背景

患有阿片类药物使用障碍（OUD）的患者经常因急性药物过量和戒断症状到急诊室接受治疗。

病例介绍

一名 29 岁男性在静脉注射海洛因后意外摄入纳曲酮，随后到急诊室就诊。他接受了丁丙诺啡治疗，其临床阿片类戒断评分在数小时内从中度到轻度戒断症状显著改善。

结论

在 OUD 患者中，可使用丁丙诺啡和最小的支持性护理来治疗由口服纳曲酮引发的急性戒断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0eec/7542394/23acb1a70188/12954_2020_417_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0eec/7542394/23acb1a70188/12954_2020_417_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0eec/7542394/23acb1a70188/12954_2020_417_Fig1_HTML.jpg

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本文引用的文献

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Drug and Opioid-Involved Overdose Deaths - United States, 2017-2018.药物和阿片类药物相关过量死亡 - 美国，2017-2018 年。
MMWR Morb Mortal Wkly Rep. 2020 Mar 20;69(11):290-297. doi: 10.15585/mmwr.mm6911a4.
2
Treatment of acute naloxone-precipitated opioid withdrawal with buprenorphine.纳洛酮诱发的阿片类药物戒断的丁丙诺啡治疗。
Am J Emerg Med. 2020 Mar;38(3):691.e3-691.e4. doi: 10.1016/j.ajem.2019.09.014. Epub 2019 Nov 16.
3
Rapid induction onto sublingual buprenorphine after opioid overdose and successful linkage to treatment for opioid use disorder.
阿片类药物过量后快速舌下含服丁丙诺啡诱导，并成功与阿片类药物使用障碍治疗建立联系。
Am J Emerg Med. 2019 Dec;37(12):2259-2262. doi: 10.1016/j.ajem.2019.05.053. Epub 2019 May 29.
4
Rapid transition from methadone to buprenorphine using naltrexone-induced withdrawal: A case report.美沙酮快速转换丁丙诺啡，应用纳曲酮诱导戒断：病例报告。
Subst Abus. 2019;40(2):140-145. doi: 10.1080/08897077.2019.1573776. Epub 2019 Mar 19.
5
Elective Naloxone-Induced Opioid Withdrawal for Rapid Initiation of Medication-Assisted Treatment of Opioid Use Disorder.选择性纳洛酮诱导的阿片类药物戒断用于快速启动阿片类药物使用障碍的药物辅助治疗。
Ann Emerg Med. 2019 Sep;74(3):430-432. doi: 10.1016/j.annemergmed.2019.01.006. Epub 2019 Feb 14.
6
Managing Opioid Withdrawal in the Emergency Department With Buprenorphine.在急诊科使用丁丙诺啡管理阿片类药物戒断反应
Ann Emerg Med. 2019 May;73(5):481-487. doi: 10.1016/j.annemergmed.2018.11.032. Epub 2019 Jan 5.
7
The Clinical Opiate Withdrawal Scale (COWS).临床阿片戒断量表（COWS）。
J Psychoactive Drugs. 2003 Apr-Jun;35(2):253-9. doi: 10.1080/02791072.2003.10400007.
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Emerg Med J. 2003 Jul;20(4):381-2. doi: 10.1136/emj.20.4.381.