Liu Wei Chiang, Lim Jae Hoon, Park Cheol Keun, Kim Min Ju, Kim Seung Hoon, Lee Soon Jin, Lee Won Jae, Lim Hyo Keun
Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, 135-710, Kangnam-ku, Seoul, Korea.
Eur Radiol. 2003 Jul;13(7):1693-8. doi: 10.1007/s00330-002-1814-3. Epub 2003 Feb 5.
The objective of this study was to assess the detectability of hepatocellular carcinoma by sonography in advanced cirrhotic patients undergoing liver transplantation. We retrospectively reviewed pretransplantation sonography in 118 consecutive patients with advanced liver cirrhosis. We assessed the detectability of hepatocellular carcinoma in relation to tumor size, location, total liver volume, and degree of sonographic heterogeneity of the liver parenchyma. On pathologic examination, 51 hepatocellular carcinomas were identified in 31 patients. Pretransplantation sonography depicted 14 of 51 (27%) hepatocellular carcinomas. Detectability was significantly affected according to tumor size ( p=0.0099), but there was no significant difference according to tumor location, liver volume, or degree of sonographic heterogeneity of the liver parenchyma. Our study suggests that sonography is not sufficiently sensitive to detect hepatocellular carcinoma in patients with advanced liver cirrhosis. Tumor size is the only factor influencing the detectability of hepatocellular carcinoma.
本研究的目的是评估超声检查对接受肝移植的晚期肝硬化患者肝细胞癌的检测能力。我们回顾性分析了118例连续的晚期肝硬化患者的移植前超声检查结果。我们评估了肝细胞癌的检测能力与肿瘤大小、位置、肝脏总体积以及肝实质超声异质性程度之间的关系。病理检查发现，31例患者中有51个肝细胞癌。移植前超声检查发现了51个肝细胞癌中的14个（27%）。检测能力根据肿瘤大小受到显著影响（p=0.0099），但根据肿瘤位置、肝脏体积或肝实质超声异质性程度没有显著差异。我们的研究表明，超声检查对晚期肝硬化患者肝细胞癌的检测不够敏感。肿瘤大小是影响肝细胞癌检测能力的唯一因素。
