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[HIV感染的临床表现及分类问题]

[Clinical manifestations and the problems of classification of HIV infection].

作者信息

Iurin O G, Irova T I, Gabrilovich D I, Suvorova Z K, Kravchenko A V, Potekaev N S, Kharchenko O I, Pokrovskiĭ V V

出版信息

Vestn Ross Akad Med Nauk. 1992(9-10):16-9.

PMID:1283710
Abstract

The clinical manifestations and some immunological parameters (CD4 lymphocytes, CD4/CD8 ratio, IgM, IgA, IgG levels, skin test) were examined in 226 adult patients (148 males and 78 females) infected with HIV. These included 58 (26%) asymptomatic patients with seropositive test, 109 (48%) with the only clinical manifestation generalized lymphadenopathy; 54 (24%) with AIDS-related infections, 5 (2%) with AIDS. A subsequent follow-up of 3 months to 3 years demonstrated that AIDS developed in 7 patients, 9 died. The period of infection with HIV and death ranged from 1.5 to 9 years. The signs of cell immunodeficiency were found in 70% of the examinees. Recommendations are given on the classification of HIV infection.

摘要

对226例感染HIV的成年患者(148例男性和78例女性)的临床表现及一些免疫学参数(CD4淋巴细胞、CD4/CD8比值、IgM、IgA、IgG水平、皮肤试验)进行了检查。其中包括58例(26%)血清学检测呈阳性的无症状患者,109例(48%)仅有全身淋巴结肿大这一临床表现的患者;54例(24%)患有艾滋病相关感染的患者,5例(2%)患有艾滋病的患者。随后进行的3个月至3年的随访表明,7例患者发展为艾滋病,9例死亡。感染HIV至死亡的时间为1.5至9年。70%的受检者存在细胞免疫缺陷迹象。文中给出了关于HIV感染分类的建议。

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