Abena A A, Miguel L M, Mouanga A, Hondi Assah Th, Diatewa M
Laboratory of Biochemistry and Pharmacology, Faculty of Health Sciences, University Marien Ngouabi, BP 69, Brazzaville, Congo.
Fitoterapia. 2003 Jul;74(5):486-8. doi: 10.1016/s0367-326x(03)00124-2.
The aqueous extracts of Datura fastuosa leaves and seeds were evaluated for the analgesic effect on acetic acid-induced writhing and hot plate reaction in mice. According to the results, D. fastuosa leaves and seeds extracts at oral doses of 400 and 800 mg/kg are effective as analgesic. The analgesic activity of leaf extract is reduced by naloxone but not that of seed extract.
对白花曼陀罗叶和种子的水提取物进行了评估，观察其对小鼠醋酸诱导扭体反应和热板反应的镇痛作用。结果显示，口服剂量为400和800 mg/kg的白花曼陀罗叶和种子提取物具有有效的镇痛作用。叶提取物的镇痛活性可被纳洛酮降低，但种子提取物的镇痛活性不受影响。
