Esenwein S A, Horch C, Meindl R, Muhr G, Bötel Dagger U
Berufsgenossenschaftliche Kliniken Bergmannsheil, Universitätsklinik der Ruhr-Universität Bochum, Chirurgische Klinik mit Poliklinik, Bochum, Germany.
Zentralbl Neurochir. 2003;64(2):80-5. doi: 10.1055/s-2003-40377.
Although the presence of an intramedullary abscess of the spinal cord is extremely rare, it is most important to be aware of its existence in the differential diagnosis of neurological diseases. Existing neurological deficits with progressive symptoms of paraplegia should always be regarded as suspect and a differential diagnosis of an intramedullary abscess of the spinal cord should then be included in the therapeutical regimen. A correct diagnosis using MR-tomography followed by an early surgical treatment strategy are essential for the affected patients, simply because an early diagnosis and an immediate operative intervention represent decisive prognostic factors independent from the cause of infection. Surgical intervention must include a decompressive laminectomy, a myelotomy, and also a secure intraoperative abscess drainage. In this analysis two patients will be reported on, both of whom were already showing symptoms of paraplegia at the time they were admitted to hospital. In both cases MR-tomographically an intramedullary nodulary lesion of the spinal cord could be detected. However, due to a complete lack of any acute symptoms of inflammatory reaction in one patient, an intramedullary abscess was not actually diagnosed before surgical treatment was performed. These two cases, together with existing scientific literature, aim to present an overview of the pathogenesis, the clinical symptomatology, the treatment strategy, and the expected therapeutical outcome of an intramedullary abscess formation. It will be shown that by treating this disease as early as possible using adequate therapeutic interventions a functional improvement of the resulting neurological symptoms can be expected.
虽然脊髓髓内脓肿极为罕见,但在神经系统疾病的鉴别诊断中,了解其存在至关重要。出现伴有截瘫进行性症状的现有神经功能缺损时,应始终视为可疑情况,随后在治疗方案中应纳入脊髓髓内脓肿的鉴别诊断。对患者而言,采用磁共振断层扫描进行正确诊断并随后采取早期手术治疗策略至关重要,这是因为早期诊断和立即手术干预是独立于感染原因的决定性预后因素。手术干预必须包括减压性椎板切除术、脊髓切开术,以及术中安全的脓肿引流。在本分析中,将报告两名患者,他们入院时均已出现截瘫症状。在这两个病例中,磁共振断层扫描均检测到脊髓髓内结节性病变。然而,其中一名患者完全没有任何炎症反应的急性症状,因此在进行手术治疗之前实际上并未诊断出髓内脓肿。这两个病例以及现有的科学文献旨在概述脊髓髓内脓肿形成的发病机制、临床症状、治疗策略以及预期的治疗结果。结果将表明,通过尽早使用适当的治疗干预措施治疗这种疾病,可以预期所导致的神经症状会有功能改善。