Department of Neurological Surgery and Neuroradiology, University of Miami/Jackson Memorial Hospital, Miami, Florida, USA.
World Neurosurg. 2011 Sep-Oct;76(3-4):361.e15-9. doi: 10.1016/j.wneu.2010.01.013.
An intramedullary spinal cord abscess is a rare, albeit widely publicized entity. Classically, patients have an acute onset of symptoms with fevers and leukocytosis supporting the diagnosis. We present a case of intramedullary spinal cord without classic history or imaging characteristics in which the diagnosis was made with diffusion weighted magnetic resonance imaging (MRI).
A 57-year-old physician presented with severe neck and shoulder pain, which progressed over several days to right-sided hemiparesis with dysesthesias. There was no history of fevers, rigors, or illness. A contrast enhanced MRI of the cervical spine revealed an intramedullary lesion centered around C6-T1 that showed peripheral enhancement with gadolinium and edema extending rostrally and caudally. He was then transferred to our institution where the novel application of diffusion weighted MRI of the spinal cord was performed, suggesting an abscess. He then underwent focal laminectomies and biopsy of this lesion with drainage of the necrotic cavity. Intraoperative Gram stain revealed gram-positive cocci, and cultures were sent to the laboratory. After draining the purulent material and completing a course of tailored antibiotics, the patient showed improvement of his neurologic deficit.
The use of diffusion weighted imaging in the spine is a novel application of technology that provided an accurate preoperative diagnosis and allowed us to tailor our surgical approach and provide a rapid focal decompression.
脊髓髓内脓肿是一种罕见但广泛报道的疾病。经典情况下,患者有急性起病的症状,发热和白细胞增多支持诊断。我们报告一例无典型病史或影像学特征的脊髓髓内脓肿,其诊断依赖于弥散加权磁共振成像(MRI)。
一名 57 岁医生出现严重的颈部和肩部疼痛,数天后进展为右侧偏瘫伴感觉异常。无发热、寒战或疾病史。颈椎增强 MRI 显示 C6-T1 为中心的脊髓内病变,钆增强显示周边强化,水肿向头端和尾端延伸。然后他被转至我们的机构,对脊髓进行了弥散加权 MRI 的新应用,提示为脓肿。然后他接受了局部椎板切除术和该病变的活检,并引流坏死腔。术中革兰氏染色显示革兰氏阳性球菌,培养物被送到实验室。在排出脓性物质并完成适当抗生素疗程后,患者的神经功能缺损得到改善。
弥散加权成像在脊柱中的应用是一种新技术的新颖应用,它提供了准确的术前诊断,并使我们能够调整手术方法,提供快速的局部减压。