Matsumura K, Matsumoto Y, Komiyama M
Department of Industrial Chemistry, Faculty of Engineering, University of Tokyo, Japan.
Nucleic Acids Symp Ser. 1992(27):11-2.
Adenylyl(3'-5')adenosine (ApA) and uridyl(3'-5')uridine (UpU) are hydrolyzed at unprecedentedly large rates by rare earth metal ions at pH 8, 30 degrees C. With 0.01 M Tm(III), the half-lives are 10 min and 51 min, respectively. Potentiality of these ions as catalytic center of artificial ribonuclease is proposed.
腺苷（3'-5'）腺苷（ApA）和尿苷（3'-5'）尿苷（UpU）在pH 8、30℃条件下，被稀土金属离子以前所未有的高速率水解。在0.01 M铥（III）存在时，半衰期分别为10分钟和51分钟。有人提出这些离子作为人工核糖核酸酶催化中心的可能性。
