Spitzer D, Steiner H, Batka M, Staudach A
Landesfrauenklinik Salzburg.
Z Geburtshilfe Perinatol. 1992 Nov-Dec;196(6):244-6.
33 patients with tubal pregnancy and beta-HCG level less than 2500 mIU/ml were treated with local, laparoscopic Prostaglandin-injection. Re-operation was not necessary and beta-HCG fell to undetectable levels in 73% (p = 0.05). Serial beta-HCG correlated poorly with outcome. In patients with an increasing beta-HCG success was limited to 55% (p = 0.59). In contrast patients with falling or stable beta-HCG values had success rates of 85.7% (p = 0.22) and 83.5% (p = 0.30) respectively. Our data suggests there may be a clinical advantage to the use of prostaglandin-injection for the conservative management of early ectopic pregnancy. However the utility of preoperative serial beta-HCG values in predicting success showed a trend, without reaching statistical significance.
33例输卵管妊娠且β-HCG水平低于2500 mIU/ml的患者接受了局部腹腔镜前列腺素注射治疗。无需再次手术，73%的患者β-HCG降至检测不到的水平（p = 0.05）。连续检测的β-HCG与治疗结果的相关性较差。β-HCG升高的患者成功率仅为55%（p = 0.59）。相比之下，β-HCG值下降或稳定的患者成功率分别为85.7%（p = 0.22）和83.5%（p = 0.30）。我们的数据表明，前列腺素注射用于早期异位妊娠的保守治疗可能具有临床优势。然而，术前连续β-HCG值在预测治疗成功方面虽有一定趋势，但未达到统计学意义。
