肯尼亚内罗毕持续性输卵管卵巢脓肿的病因
Etiology of persistent tubo-ovarian abscess in Nairobi, Kenya.
作者信息
Cohen Craig R, Gravelle Lisa, Symekher Samwel, Waiyaki Peter, Stamm Walter E, Kiehlbauch Julia A
机构信息
Department of Obstetrics and Gynecology, University of Washington, Seattle, WA 98195-6460, USA.
出版信息
Infect Dis Obstet Gynecol. 2003;11(1):45-51. doi: 10.1155/S1064744903000061.
OBJECTIVE
To study the microbial etiology of tubo-ovarian abscess (TOA).
METHODS
We recruited 11 women in Nairobi, Kenya who failed antibiotic therapy alone and required surgical drainage of a presumptive TOA. Pus from the nine abscesses and two pyosalpinges were collected and cultured for aerobic, facultative and anaerobic microorganisms.
RESULTS
Eleven women suspected of having a TOA were hospitalized and treated for a median of 6 days (range 3-14 days) prior to surgical drainage of the abscess. Nine (82%) specimens were culture positive. Aerobes were present in all nine specimens. Seven of the nine positive cultures (78%) were polymicrobial and five of the polymicrobial cultures contained both anaerobes and aerobes. Anaerobic Gram-negative bacilli (Prevotella sp., Porphyromonas sp. and Bacteroides sp., Escherichia coli) and Streptococcus sp. (S. viridans and S. agalactiae) were the most common microorganisms isolated. Neisseria gonorrhoeae and Chlamydia trachomatis were not isolated by culture or detected by polymerase chain reaction.
CONCLUSIONS
In Kenya, persistent TOAs are associated with endogenous flora similar to that normally found in the gastrointestinal tract.
目的
研究输卵管卵巢脓肿（TOA）的微生物病因。
方法
我们招募了肯尼亚内罗毕的11名女性，她们单独使用抗生素治疗失败，需要对疑似TOA进行手术引流。收集了9个脓肿和2个输卵管积脓的脓液，培养需氧、兼性和厌氧微生物。
结果
11名疑似患有TOA的女性在脓肿手术引流前住院治疗，中位时间为6天（范围3 - 14天）。9份（82%）标本培养呈阳性。所有9份标本中均有需氧菌。9份阳性培养物中有7份（78%）为混合菌感染，其中5份混合菌培养物同时含有厌氧菌和需氧菌。厌氧革兰氏阴性杆菌（普雷沃菌属、卟啉单胞菌属、拟杆菌属、大肠杆菌）和链球菌属（草绿色链球菌和无乳链球菌）是最常见的分离微生物。淋病奈瑟菌和沙眼衣原体未通过培养分离或通过聚合酶链反应检测到。
结论
在肯尼亚，持续性TOA与胃肠道中正常存在的内源性菌群有关。
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