Ricchi E, Borderi M, Costigliola P, Miniero R, Sprovieri G, Chiodo F
Istituto Malattie Infettive, Università di Bologna, Italy.
Eur J Epidemiol. 1992 Nov;8(6):804-7. doi: 10.1007/BF00145323.
The authors report on an anti-hepatitis C virus antibody (HCV Ab) prevalence (6.9%) in 622 homo-bisexual males from Northern Italy, voluntarily attending an HIV and STDs screening program in the period 1984-89. The anti-HCV antibody prevalence shows a significant correlation with: i) presence of serological markers for HBV (O.R. = 3.12, 95% C.I. = 1.53-6.52) and HIV (O.R. = 12.09; C.I. = 6.52-22.52) infection; ii) a stable relationship with an anti-HCV antibody positive partner (O.R. = 7.79; 95% C.I. = 2.50-23.90); iii) more than twenty different male partners per year (O.R. = 2.55; 95% C.I. = 1.17-5.66). These data demonstrate the existence of a sexual transmission of HCV among homosexuals. This route might contribute in maintaining endemic levels of HCV infection in the homo-bisexual population and it might represent an important way of spreading the virus in the general population too.
作者报告了1984年至1989年期间，622名来自意大利北部的男同性恋者自愿参加艾滋病毒和性传播疾病筛查项目时的抗丙型肝炎病毒抗体（HCV Ab）流行率（6.9%）。抗HCV抗体流行率与以下因素显著相关：i）乙肝血清学标志物（比值比=3.12，95%可信区间=1.53-6.52）和艾滋病毒（比值比=12.09；可信区间=6.52-22.52）感染的存在；ii）与抗HCV抗体阳性伴侣保持稳定关系（比值比=7.79；95%可信区间=2.50-23.90）；iii）每年有超过20个不同的男性伴侣（比值比=2.55；95%可信区间=1.17-5.66）。这些数据证明了丙型肝炎病毒在同性恋者中存在性传播。这种传播途径可能有助于维持男同性恋人群中丙型肝炎病毒感染的流行水平，也可能是该病毒在普通人群中传播的重要途径。
