具有发夹结构的补骨脂素共轭寡核苷酸作为一种新型光敏反义分子。
Psoralen-conjugated oligonucleotide with hairpin structure as a novel photo-sensitive antisense molecule.
作者信息
Yamayoshi Asako, Iwase Reiko, Yamaoka Tetsuji, Murakami Akira
机构信息
Department of Polymer Science and Engineering, Kyoto Institute of Technology, Matsugasaki, Kyoto 606-8585, Japan.
出版信息
Chem Commun (Camb). 2003 Jun 21(12):1370-1. doi: 10.1039/b302291a.
DOI:10.1039/b302291a
PMID:12841246
Abstract
Hairpin type psoralen-cojugated oligonucleotides cross-linked with RNA when they hybridized with a perfectly complementary RNA.
摘要
发夹型补骨脂素共轭寡核苷酸在与完全互补的RNA杂交时会与RNA交联。
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