Wood Douglas E, Liu Yun-Hen, Vallières Eric, Karmy-Jones Riyad, Mulligan Michael S
Section of General Thoracic Surgery, University of Washington, Seattle, Washington 98195-6310, USA.
Ann Thorac Surg. 2003 Jul;76(1):167-72; discussion 173-4. doi: 10.1016/s0003-4975(03)00033-x.
Patients with benign and malignant central airway obstruction suffer from disabling dyspnea, obstructive pneumonia, and impending suffocation. Therapeutic bronchoscopy provides immediate and gratifying palliation. Airway stenting is the principal modality used to manage intrinsic tracheobronchial pathology and extrinsic airway compression. This report provides the details of the indications, techniques, and results of airway stenting in our practice.
University of Washington patients undergoing bronchoscopy with stent placement or revision from May 1992 through December 2001 were extracted from a prospective patient database. Details of the stent procedure were obtained from the medical records and office charts. Early outcomes were assessed by patient symptoms and signs, and late outcomes were assessed by patient follow-up visits, follow-up bronchoscopy, or discussions, or a combination of these with the patient, patient's family, or referring physician.
One hundred forty-three patients underwent 309 stent procedures of which 67% were for malignant disease. Eighty-two percent required urgent or emergent intervention, and 77% had compromise of more than three fourths of the airway lumen. Eighty-seven percent of stents placed were silicone rubber and 15% of patients required multiple stents to achieve airway palliation. Significant improvement was achieved in 94% of patients but required multiple endoscopies to maintain improvement in 41%. There was no stent-related mortality and only one major complication required surgery.
Airway stenting provides prompt and durable palliation in unresectable patients with central airway obstruction. Frequently multiple stents and multiple procedures will be necessary to maintain a satisfactory airway.
患有良性和恶性中央气道阻塞的患者会出现严重的呼吸困难、阻塞性肺炎及濒死窒息感。治疗性支气管镜检查能迅速带来令人满意的缓解效果。气道支架置入是处理气管支气管内在病变及外在气道压迫的主要方式。本报告详述了我们在实践中气道支架置入的适应证、技术及结果。
从一个前瞻性患者数据库中提取1992年5月至2001年12月在华盛顿大学接受支气管镜检查并置入或更换支架的患者。从病历和门诊病历中获取支架置入过程的详细信息。早期结果通过患者症状和体征进行评估,晚期结果通过患者随访、随访支气管镜检查或讨论,或与患者、患者家属或转诊医生综合这些方式进行评估。
143例患者接受了309次支架置入手术,其中67%用于恶性疾病。82%的患者需要紧急或急诊干预,77%的患者气道管腔有超过四分之三的狭窄。置入的支架87%为硅橡胶材质,15%的患者需要多个支架来实现气道缓解。94%的患者有显著改善,但41%的患者需要多次内镜检查来维持改善效果。没有与支架相关的死亡病例,只有一例严重并发症需要手术治疗。
气道支架置入为无法切除的中央气道阻塞患者提供了迅速且持久的缓解。通常需要多个支架和多次手术来维持满意的气道状况。