Aravena Carlos, Gildea Thomas R
Department of Respiratory Diseases, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.
Department of Pulmonary, Allergy, and Critical Care Medicine, Respiratory Institute, Cleveland Clinic, Cleveland, OH, USA.
Ann Transl Med. 2023 Aug 30;11(10):360. doi: 10.21037/atm-22-2878. Epub 2022 Sep 6.
The primary function of an airway stent is to reestablish patency, impeding restenosis, supporting the tracheobronchial wall, or occluding fistulas. But stent-related complications are prevalent and can have devastating consequences. For this reason, stents are considered a last resort when there are no alternatives in treatment. Additionally, commercially available airway stents often poorly fit patients with complex airways, and they can cause various complications. At the end of the 20th century, three-dimensional (3D) printing technology was created. It has been transformative in healthcare and has been used in several applications. One of its first utilizations was the anatomical modeling of body structures that helps preoperative planning. In respiratory medicine, this technology has been essentially used in central airway diseases to produce 3D airway models and to create airway splints and prostheses. In the last decade, it has led to a transformation and allowed progress in personalized medicine, making patient-specific stents for individuals with complex airway problems. A patient-specific stent using 3D printing may minimize complications, improve quality of life, and reduce the need for repeated procedures. This review describes the recent advances in 3D printing technology, its use for developing airway prostheses to treat complex airway diseases, and the current evidence that supports its use.
气道支架的主要功能是重建通畅性、防止再狭窄、支撑气管支气管壁或封堵瘘管。但与支架相关的并发症很常见,可能会产生严重后果。因此,在没有其他治疗选择时,支架被视为最后的手段。此外,市售的气道支架通常与气道复杂的患者匹配不佳,并且会引发各种并发症。20世纪末,三维(3D)打印技术问世。它在医疗保健领域具有变革性,已被应用于多个方面。其最初的应用之一是身体结构的解剖建模,有助于术前规划。在呼吸医学中,这项技术主要用于中央气道疾病,以制作3D气道模型并制造气道夹板和假体。在过去十年中,它带来了变革,推动了个性化医疗的发展,为气道问题复杂的个体制造定制支架。使用3D打印的定制支架可以将并发症降至最低,提高生活质量,并减少重复手术的需求。本综述描述了3D打印技术的最新进展、其在开发气道假体以治疗复杂气道疾病方面的应用,以及支持其使用的现有证据。