Woo Patrick C Y, Ngan Antonio H Y, Lau Susanna K P, Yuen Kwok-Yung
Department of Microbiology, The University of Hong Kong, Hong Kong.
J Clin Microbiol. 2003 Jul;41(7):3368-71. doi: 10.1128/JCM.41.7.3368-3371.2003.
In this report, we describe the first three cases of Tsukamurella conjunctivitis in the literature. All three patients presented with congestion of one eye with small amounts of serous discharge for 1 to 2 days. All three recovered after 10 days of treatment with polymyxin B-neomycin or chloramphenicol eyedrops. Sequencing of the 16S rRNA genes of the three isolates recovered from the serous discharge of the three patients showed that they were all Tsukamurella species. The phenotypic characteristics of the isolate obtained from one patient best fit the phenotypic profile of Tsukamurella pulmonis, whereas those of the other two best fit that of Tsukamurella tyrosinosolvens.
在本报告中,我们描述了文献中首例三例冢村菌属结膜炎病例。所有三名患者均表现为单眼充血,伴有少量浆液性分泌物,持续1至2天。所有三名患者在使用多粘菌素B - 新霉素或氯霉素滴眼液治疗10天后均康复。对从三名患者的浆液性分泌物中分离出的三株菌株的16S rRNA基因进行测序,结果显示它们均为冢村菌属。从一名患者分离出的菌株的表型特征与肺冢村菌的表型特征最为匹配,而另外两名患者的菌株表型特征则与解酪冢村菌最为匹配。