Kim Y S, Pai C H, Chi H S, Kim D W, Min Y I, Ahn Y O
Department of Family Medicine, College of Medicine, University of Ulsan, Korea.
J Korean Med Sci. 1992 Dec;7(4):333-6. doi: 10.3346/jkms.1992.7.4.333.
To estimate the prevalence of hepatitis C virus (HCV) infection among Korean adults and to present the putative route of HCV transmission among them, serum samples from 4917 adults older than 20 years of age were tested for antibody to HCV (anti-HCV), and histories of blood transfusion and other pertinent information were obtained by self-administered questionnaires. The overall prevalence of anti-HCV was 1.7%; prevalence was 1.4% in subjects with normal levels of aspartate aminotransferase (AST) and alanine aminotransferase (ALT), 3.3% in those with slightly elevated and 5.9% in those with markedly elevated levels of the enzymes. The prevalence of anti-HCV increased with increasing age (P < 0.01), but was not associated with blood transfusion. The present study suggests that the prevalence of HCV infection was 1.4% and that the major routes of HCV transmission may be other than blood transfusion in healthy Korean adults.
为了评估韩国成年人丙型肝炎病毒（HCV）感染的流行率，并揭示其可能的传播途径，我们对4917名20岁以上成年人的血清样本进行了抗HCV检测，并通过自填式问卷获取了输血史及其他相关信息。抗HCV的总体流行率为1.7%；天冬氨酸转氨酶（AST）和丙氨酸转氨酶（ALT）水平正常的受试者中流行率为1.4%，轻度升高者中为3.3%，显著升高者中为5.9%。抗HCV的流行率随年龄增长而增加（P < 0.01），但与输血无关。本研究表明，在健康的韩国成年人中，HCV感染的流行率为1.4%，且HCV的主要传播途径可能不是输血。
