Nowak C, Bourgin P, Portier F, Genty E, Escourrou P, Bobin S
Service ORL, CHU de Bicêtre, 78 avenue du Général Leclerc, 94275 Kremlin Bicêtre Cedex.
Ann Otolaryngol Chir Cervicofac. 2003 Jun;120(3):161-6.
Obstructive sleep apnea syndrome is a very common disease. Nasal continuous positive airway pressure is a useful and efficient treatment but compliance depends on several factors including the degree of nasal obstruction.
The aim of this study was to evaluate the effects of surgical correction of nasal obstruction on compliance to nasal continuous positive airway pressure in obstructive sleep apnea syndrome.
This retrospective study (from March 1998 to March 2000) included ten patients suffering from a severe obstructive sleep apnea syndrome (apnea-hypopnea index greater than 30 per hour) treated by nasal continuous positive airway pressure for at least three months and presenting an anatomic nasal obstruction limiting the use of nasal continuous positive airway pressure. Surgical procedures included one septoplasty, two inferior turbinectomies and seven septoplasties with turbinectomies.
The post-operative polysomnography showed that surgical correction of nasal obstruction had no effect on obstructive sleep apnea syndrome severity (no significative change of apnea hypopnea index after surgery) but allowed the use of lower nasal continuous positive airway pressure levels (7.1 mmHg after surgery versus 10 mmHg before) and improved compliance to treatment (six compliant patients after surgery versus no compliant patient before). These results were compared with those published in the literature.
An examination of the nose has to be performed before initiating nasal continuous positive airway pressure. If nasal continuous positive airway pressure cannot be tolerated because of nasal obstruction, surgery is required to improve compliance and tolerance to treatment.
阻塞性睡眠呼吸暂停综合征是一种非常常见的疾病。鼻持续气道正压通气是一种有效且实用的治疗方法,但依从性取决于包括鼻阻塞程度在内的多个因素。
本研究旨在评估鼻阻塞手术矫正对阻塞性睡眠呼吸暂停综合征患者鼻持续气道正压通气依从性的影响。
这项回顾性研究(1998年3月至2000年3月)纳入了10例患有严重阻塞性睡眠呼吸暂停综合征(呼吸暂停低通气指数每小时大于30次)的患者,这些患者接受鼻持续气道正压通气治疗至少3个月,且存在解剖学鼻阻塞限制了鼻持续气道正压通气的使用。手术操作包括1例鼻中隔成形术、2例下鼻甲切除术以及7例鼻中隔成形术联合下鼻甲切除术。
术后多导睡眠图显示,鼻阻塞的手术矫正对阻塞性睡眠呼吸暂停综合征的严重程度没有影响(术后呼吸暂停低通气指数无显著变化),但允许使用更低水平的鼻持续气道正压通气(术后为7.1 mmHg,术前为10 mmHg),并提高了治疗依从性(术后6例依从患者,术前无依从患者)。这些结果与文献中发表的结果进行了比较。
在开始鼻持续气道正压通气之前必须对鼻子进行检查。如果因鼻阻塞而无法耐受鼻持续气道正压通气,则需要进行手术以提高治疗依从性和耐受性。