Uwabe Y, Yoshida H, Onishi M, Kudo K, Motoyoshi K, Aida S, Nagata N
Third Department of Internal Medicine, National Defense Medical College, Saitama, Japan.
Intern Med. 1992 Dec;31(12):1387-91. doi: 10.2169/internalmedicine.31.1387.
A 33-year-old Japanese woman visited our hospital with progressive dyspnea. A chest roentgenogram and a chest computed tomogram revealed a mediastinal tumor and pericardial effusion. Ultrasound cardiography revealed the existence of cardiac tamponade. She was successfully treated with emergency pericardial drainage, thoracocentesis and chemotherapy. The histological diagnosis of diffuse large B cell lymphoma was established with the tumor specimen obtained by transcutaneous fine needle aspiration biopsy and through immunohistochemical analysis. This is a rare case of primary mediastinal diffuse large cell lymphoma with initial presentation of a symptom related to pericardial effusion.
一名33岁的日本女性因进行性呼吸困难前来我院就诊。胸部X线片和胸部计算机断层扫描显示纵隔肿瘤和心包积液。超声心动图显示存在心脏压塞。她通过紧急心包引流、胸腔穿刺和化疗得到了成功治疗。通过经皮细针穿刺活检获得的肿瘤标本并经免疫组织化学分析，确诊为弥漫性大B细胞淋巴瘤。这是一例罕见的原发性纵隔弥漫性大细胞淋巴瘤，最初表现为与心包积液相关的症状。
