Hsiao Chien-Chou, Tsao Lon-Yen, Chen Hsiao-Neng
Department of Pediatrics, Changhua Christian Hospital, No. 135, Nan-Siau Street, Changhua 500, Taiwan.
Acta Paediatr Taiwan. 2003 Mar-Apr;44(2):104-5.
Neonates infected with nonpolio enteroviruses are at high risk for developing significant illness, including sepsis-like illness, meningoencephalitis, myocarditis and/or hepatitis. Echoviruses and group B coxsackieviruses account for the majority of neonatal enterovirus infections. We reported a case of echovirus 11 infection in newborn associated with maternal infection. To our knowledge, this is the first reported fatal case of neonatal echovirus infection in Taiwan. Eventually, the baby expired because of severe sepsis-like illness, fulminant hepatitis, disseminated intravascular coagulation, and extensive hemorrhagic manifestations in spite of intensive care, intravenous immunoglobulin infusion and exchange transfusion.
感染非脊髓灰质炎肠道病毒的新生儿发生严重疾病的风险很高，包括败血症样疾病、脑膜脑炎、心肌炎和/或肝炎。埃可病毒和B组柯萨奇病毒占新生儿肠道病毒感染的大多数。我们报告了1例与母亲感染相关的新生儿埃可病毒11感染病例。据我们所知，这是台湾地区首例报告的新生儿埃可病毒感染死亡病例。最终，尽管进行了重症监护、静脉注射免疫球蛋白和换血治疗，婴儿仍因严重的败血症样疾病、暴发性肝炎、弥散性血管内凝血和广泛的出血表现而死亡。
