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可卡因暴露后母婴的医疗保健利用情况。

Health-care utilization among mothers and infants following cocaine exposure.

作者信息

Shankaran Seetha, Bauer Charles R, Bada Henrietta S, Lester Barry, Wright Linda L, Das Abhik

机构信息

Wayne State University, Detroit, MI, USA.

出版信息

J Perinatol. 2003 Jul-Aug;23(5):361-7. doi: 10.1038/sj.jp.7210946.

Abstract

OBJECTIVE

To examine utilization of health-care resources among mothers and infants following cocaine use during pregnancy.

DESIGN

Prospective observational study.

SETTING

Four clinical sites.

PATIENTS/METHODS: Medical and social services resource use was examined among 8514 mother-infant dyads, 1072 of whom used cocaine and 7442 who did not. Use was stratified by <1500 g and >1500 g birth-weight strata to differentiate the low birth weight from the larger weight group adjusting for site, infant gender, and maternal race and education.

OUTCOME MEASURES

Resource use evaluated among mothers included prenatal care, hospitalizations, medications and mode of delivery. Resource use for infants included therapies, procedures and length of stay.

RESULTS

Fewer cocaine-exposed women, compared to those in the nonexposed group, had prenatal care or used medications during pregnancy in both <1500 g category 0.10 (0.04 to 0.22) (OR (99% CI) and 0.26 (0.10 to 0.65), respectively, and in the >1500 g category 0.14 (0.11 to 0.19) and 0.61 (0.49 to 0.74), respectively. Length of hospital stay for social reasons and referrals to child protective services were increased in cocaine-exposed infants in both <1500 g category 66.8 (4.38 to 999.9) and 77.4 (17.64 to 289.13), respectively and in the >1500 g category 70.74 (41.73 to 119.94) and 125.88 (81.78 to 193.77), respectively. In addition, among >1500 g cocaine-exposed infants, length of stay in neonatal intensive care unit was increased 1.53 (1.16 to 2.02) as was therapies 1.76 (1.45 to 2.13), procedures 1.50 (1.23 to 1.83), need for formula feeds 5.45 (2.28 to 13.02) and intravenous fluids 1.50 (1.19 to 1.87),

CONCLUSION

Cocaine exposure has no deleterious or protective effects on medical resource needs of <1500 g infants or their mothers. Resource needs reflect those of morbidity of being born premature. The increase in health-care resources for >1500 g cocaine-exposed infants for surveillance and monitoring in the absence of an increase in congenital anomalies should be discouraged.

摘要

目的

研究孕期使用可卡因的母婴对医疗资源的利用情况。

设计

前瞻性观察性研究。

地点

四个临床场所。

患者/方法:对8514对母婴进行了医疗和社会服务资源利用情况调查,其中1072对母婴使用了可卡因,7442对未使用。根据出生体重<1500克和>1500克分层,以区分低出生体重组和较大体重组,并对场所、婴儿性别、母亲种族和教育程度进行了调整。

观察指标

评估母亲的资源利用情况包括产前护理、住院、用药和分娩方式。婴儿的资源利用情况包括治疗、操作和住院时间。

结果

与未接触可卡因的女性相比,接触可卡因的女性在<1500克组中接受产前护理或孕期用药的比例分别为0.10(0.04至0.22)(OR(99%CI))和0.26(0.10至0.65),在>1500克组中分别为0.14(0.11至0.19)和0.61(0.49至0.74)。<1500克组中,因社会原因住院时间和转介至儿童保护服务机构的情况在接触可卡因的婴儿中有所增加,分别为66.8(4.38至999.9)和77.4(17.64至289.13),在>1500克组中分别为70.74(41.73至119.94)和125.88(8至193.77)。此外,在>1500克接触可卡因的婴儿中,新生儿重症监护病房的住院时间增加了1.53(1.16至2.02),治疗增加了1.76(1.45至2.13),操作增加了1.50(1.23至1.83),需要配方奶喂养的情况增加了5.45(2.28至13.02),静脉输液增加了1.50(1.19至1.87)。

结论

可卡因暴露对<1500克婴儿或其母亲的医疗资源需求没有有害或保护作用。资源需求反映了早产发病的情况。对于>1500克接触可卡因的婴儿,在先天性异常没有增加的情况下,不应鼓励增加用于监测的医疗资源。

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