Shankaran Seetha, Lester Barry M, Das Abhik, Bauer Charles R, Bada Henrietta S, Lagasse Linda, Higgins Rosemary
Wayne State University School of Medicine, Detroit, MI, USA.
Semin Fetal Neonatal Med. 2007 Apr;12(2):143-50. doi: 10.1016/j.siny.2007.01.002. Epub 2007 Feb 20.
The impact of maternal substance abuse is reflected in the 2002-2003 National Survey on Drug Use and Health. Among pregnant women in the 15-44 age group, 4.3%, 18% and 9.8% used illicit drugs, tobacco and alcohol, respectively. Maternal pregnancy complications following substance use include increases in sexually transmitted disorders, placental abruption and HIV-positive status. Effects on the neonate include a decrease in growth parameters and increases in central nervous system and autonomic nervous system signs and in referrals to child protective agencies. In childhood, behavioral and cognitive effects are seen after prenatal cocaine exposure; tobacco and alcohol have separate and specific effects. The ongoing use of alcohol and tobacco by the caretaker affects childhood behavior. Therefore, efforts should be made to prevent and treat behavioral problems as well as to limit the onset of drug use by adolescent children born to women who use drugs during pregnancy.
2002 - 2003年全国药物使用和健康调查反映了母亲药物滥用的影响。在15 - 44岁年龄组的孕妇中,分别有4.3%、18%和9.8%的人使用非法药物、烟草和酒精。母亲使用药物后出现的妊娠并发症包括性传播疾病增加、胎盘早剥和艾滋病毒阳性状态。对新生儿的影响包括生长参数下降、中枢神经系统和自主神经系统体征增加以及转介至儿童保护机构的情况增多。在儿童期,产前接触可卡因后会出现行为和认知方面的影响;烟草和酒精有各自特定的影响。照顾者持续使用酒精和烟草会影响儿童行为。因此,应努力预防和治疗行为问题,并限制孕期吸毒妇女所生青春期子女的吸毒行为发生。