Khrushchov N G
Izv Akad Nauk Ser Biol. 1992 May-Jun(3):325-33.
The data are summarized on comparative investigations by the author and co-workers concerning regenerative process in hemopoietic and connective tissues of representatives of molluscs, cyclostomes, fishes and mammals. In gastropods, a regeneration stimulus strikingly increases the volume of amebocyte reproduction foci in the pericardium (primitive organ of hemopoiesis), accelerates the amebocyte yield into the peripheral blood and induces the appearance of DNA-synthesizing cells in the latter. The stimulation of precursor cell reproduction in hemopoietic organs and the acceleration of their maturation and yield into the peripheral blood are common processes in the regeneration response for hemopoietic systems of mammals, fishes and cyclostomes. In contrast to fishes and cyclostomes, adult mammals show the absence of dividing (DNA-synthesizing) cells and mature segmentonuclear granulocytes demonstrate neither RNA nor protein synthesis. In all forms studied, the stromal type cells of hemopoietic nature (fibroblast-like, fixed macrophages, etc.) are a constant and continuously renewed component of connective tissue and play a considerable role in its regeneration.
本文总结了作者及其同事关于软体动物、圆口纲动物、鱼类和哺乳动物造血组织及结缔组织再生过程的比较研究数据。在腹足纲动物中，再生刺激显著增加了心包（原始造血器官）中阿米巴样细胞繁殖灶的体积，加速了阿米巴样细胞进入外周血，并诱导外周血中出现DNA合成细胞。刺激造血器官中前体细胞的繁殖，加速其成熟并进入外周血，是哺乳动物、鱼类和圆口纲动物造血系统再生反应中的常见过程。与鱼类和圆口纲动物不同，成年哺乳动物不存在分裂（DNA合成）细胞，成熟的分叶核粒细胞既不进行RNA合成也不进行蛋白质合成。在所有研究的物种中，具有造血性质的基质型细胞（成纤维细胞样、固定巨噬细胞等）是结缔组织中持续存在且不断更新的成分，在其再生过程中发挥着重要作用。
