Chertkov I L, Deriugina E I, Drize N I
Vestn Akad Med Nauk SSSR. 1990(9):35-7.
A complex of experimental original laboratory findings is presented to demonstrate a restricted proliferative potential of stem hemopoietic cells. Development of new methodologies to study primitive stem hemopoietic cells, i. e. the cells that are responsible for maintenance of continuous blood formation, allowed for confirming their existence, assessing their content in the hemopoietic tissue, determining the time and site of their embryonic origin, and for showing their limited capacity for regeneration. The obtained evidence is important for the understanding the mechanisms governing hemopoiesis.
本文展示了一系列实验性的原始实验室研究结果,以证明造血干细胞的增殖潜力有限。研究原始造血干细胞(即负责维持持续造血的细胞)的新方法的发展,使得确认它们的存在、评估它们在造血组织中的含量、确定它们胚胎起源的时间和部位以及显示它们有限的再生能力成为可能。所获得的证据对于理解造血调控机制很重要。