Zhao Y R, Zhang D F, Pan C Q
Chong qing University of Medical Sciences.
Zhonghua Nei Ke Za Zhi. 1992 Nov;31(11):686-8, 730.
Viral markers were studied in 79 cases of viral hepatitis with hepatic failure. The results were shown as follows: 8 cases were positive for anti-HAV IgM (10.12%); 76 cases positive for HBsAg or anti-HBc IgM (96.20%) and 41 cases positive for anti-HCV antibodies (51.89%). Among those with anti-HCV positive, 35 cases were co-infected with HBV, 5 cases with HAV and/or HCV, only one was infected with HCV alone 2 cases were HD-Ag positive (2.52%) and one not identified (1.27%). With the reference of clinical findings, patients co-infected with HBV/HCV or anti-HBc IgM positive were more critical and usually entail higher mortality. In cases with HCV co-infections, the positive HBV replication markers seems to be reduced. Hepatic failure without HBV replicative markers had a high rate of hepatic coma as well as poor outcome.
对79例肝衰竭的病毒性肝炎患者进行了病毒标志物研究。结果如下：抗甲型肝炎病毒IgM阳性8例（10.12%）；乙肝表面抗原或抗乙肝核心抗体IgM阳性76例（96.20%），抗丙型肝炎病毒抗体阳性41例（51.89%）。在抗丙型肝炎病毒阳性者中，35例合并乙型肝炎病毒感染，5例合并甲型肝炎病毒和/或丙型肝炎病毒感染，仅1例单独感染丙型肝炎病毒；丁型抗原阳性2例（2.52%），未明确1例（1.27%）。参照临床 findings，合并乙型肝炎病毒/丙型肝炎病毒感染或抗乙肝核心抗体IgM阳性的患者病情更严重，死亡率通常更高。在合并丙型肝炎病毒感染的病例中，乙型肝炎病毒复制标志物阳性率似乎降低。无乙型肝炎病毒复制标志物的肝衰竭患者肝昏迷发生率高，预后差。 （注：原文中“With the reference of clinical findings”这里的“findings”不太明确准确含义，暂直译为“findings”）
