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本文引用的文献

1
Influence of dose, cigarette smoking, age, sex, and metabolic activity on plasma clozapine concentrations: a predictive model and nomograms to aid clozapine dose adjustment and to assess compliance in individual patients.剂量、吸烟、年龄、性别和代谢活性对血浆氯氮平浓度的影响：一个预测模型和列线图，以辅助氯氮平剂量调整并评估个体患者的依从性。
J Clin Psychopharmacol. 2004 Feb;24(1):70-8. doi: 10.1097/01.jcp.0000106221.36344.4d.
2
Effect of post-mortem changes on peripheral and central whole blood and tissue clozapine and norclozapine concentrations in the domestic pig (Sus scrofa).死后变化对家猪（Sus scrofa）外周血和全血以及组织中氯氮平和去甲氯氮平浓度的影响。
Forensic Sci Int. 2003 Mar 12;132(1):9-17. doi: 10.1016/s0379-0738(02)00414-0.
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Human alpha-1-glycoprotein and its interactions with drugs.人α-1-糖蛋白及其与药物的相互作用。
Drug Metab Rev. 2001 May;33(2):161-235. doi: 10.1081/dmr-100104402.
4
Alpha-1-acid glycoprotein.α-1-酸性糖蛋白
Biochim Biophys Acta. 2000 Oct 18;1482(1-2):157-71. doi: 10.1016/s0167-4838(00)00153-9.
5
Therapeutic drug monitoring of clozapine: an unexpected outcome.氯氮平的治疗药物监测：一个意外结果。
Ther Drug Monit. 2000 Jun;22(3):323-4. doi: 10.1097/00007691-200006000-00015.
6
Clozapine monitoring: plasma or serum levels?氯氮平监测：血浆还是血清水平？
Ther Drug Monit. 1999 Jun;21(3):327-9. doi: 10.1097/00007691-199906000-00014.
7
Pharmacokinetics of clozapine and its metabolites in psychiatric patients: plasma protein binding and renal clearance.氯氮平及其代谢产物在精神科患者中的药代动力学：血浆蛋白结合与肾脏清除率。
Br J Clin Pharmacol. 1998 Nov;46(5):453-9. doi: 10.1046/j.1365-2125.1998.00822.x.
8
Determination of clozapine and its major metabolites in human plasma and red blood cells by high-performance liquid chromatography with ultraviolet absorbance detection.采用高效液相色谱-紫外吸收检测法测定人血浆和红细胞中的氯氮平及其主要代谢物。
J Chromatogr B Biomed Sci Appl. 1997 Mar 7;690(1-2):211-22. doi: 10.1016/s0378-4347(96)00362-3.
9
Clozapine plasma level monitoring: current status.氯氮平血药浓度监测：现状
Psychiatr Q. 1996 Winter;67(4):297-311. doi: 10.1007/BF02326373.
10
The clinical use of clozapine plasma concentrations in the management of treatment-refractory schizophrenia.氯氮平血药浓度在难治性精神分裂症治疗管理中的临床应用。
Ann Clin Psychiatry. 1996 Jun;8(2):99-109. doi: 10.3109/10401239609148808.

Comparability of whole-blood and plasma clozapine and norclozapine concentrations.

作者信息

Flanagan R J, Yusufi B, Barnes T R E

出版信息

Br J Clin Pharmacol. 2003 Jul;56(1):135-8. doi: 10.1046/j.1365-2125.2003.01821.x.

DOI:10.1046/j.1365-2125.2003.01821.x
PMID:12848787
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1884330/
Abstract
摘要