Mamalyga L M
Aviakosm Ekolog Med. 1992 Sep-Dec;26(5-6):52-5.
Effects of preliminary adaptation of rats to hypoxic hypoxia and short-term stress environments on the dynamics of the repair changes of RNA and proteins in the cellular structures of supraoptic (SON) and paraventricular (PVN) nuclei of hypothalamus are studied. Adaptation to hypoxia and short-term stresses is found to increase the potential of protein-synthetizing system of neuro- and gliocytes of SON and PVN. It prevented a marked decrease in the RNA and proteins contents during a post-stress period and increased an intensity of the repair processes in the nuclei being tested. Experimental findings are indicative of a heterochronic pattern of repair processes in hypothalamic neurosecretory structures which to a great extent can be related with their potentials to rearrange the intracellular metabolism for maximum functional maintenance during stresses.
研究了大鼠预先适应低氧性缺氧和短期应激环境对下丘脑视上核（SON）和室旁核（PVN）细胞结构中RNA和蛋白质修复变化动态的影响。发现适应缺氧和短期应激可增加SON和PVN神经细胞和神经胶质细胞蛋白质合成系统的潜力。它可防止应激后RNA和蛋白质含量显著下降，并增强受试核内修复过程的强度。实验结果表明，下丘脑神经分泌结构中修复过程存在异时模式，这在很大程度上可能与其在应激期间重新安排细胞内代谢以实现最大功能维持的潜力有关。
