Lavine Steven J, Salacata Abraham
Health Science Center, University of Florida, Jacksonville, Florida 32209, USA.
Echocardiography. 2003 Jul;20(5):401-10. doi: 10.1046/j.1540-8175.2003.03079.x.
Ejection fraction (EF) is the most commonly used parameter of left ventricular (LV) systolic function and can be assessed by echocardiography. Quantitative echocardiography is time consuming and is as accurate as visual estimation, which has significant variability. We hypothesized that each echocardiographer has developed a mental set of guidelines that relate to how much individual segment shortening constitutes normal function or hypokinesis of varying extents. We determined the accuracy of applying these guidelines to an accepted technique of EF determination using a retrospective analysis of consecutive two-dimensional echocardiographic studies performed on patients who had radioventriculography (RVG) within 48 hours. Using a 12 segment model, we scored each segment at the base and mid-ventricular level based on segmental excursion and thickening. The apex was scored similarly but with 1/3 of the value based on a cylinder-cone model. EF was determined from the sum of segment scores and was estimated visually. We termed this approach visual quantitative estimation (VQE). We correlated the EF derived from VQE and visual estimation with RVG EF. In the training set, VQE demonstrated a strong correlation with RVG (r = 0.969), which was significantly greater than visual estimation (r = 0.896, P < 0.01). The limits of agreement for VQE (+12% to -7%) were similar to the limits of RVG agreement with contrast ventriculography (+10% to -11%) with similar intraobserver and interobserver variabilities. Similar correlation was noted in the prediction set between VQE and RVG EF (r = 0.967, P < 0.001). We conclude that VQE provides highly correlated estimates of EF with RVG.
射血分数(EF)是评估左心室(LV)收缩功能最常用的参数,可通过超声心动图进行评估。定量超声心动图耗时且与视觉估计的准确性相当,而视觉估计存在显著变异性。我们假设每位超声心动图检查者都形成了一套心理准则,这些准则涉及各个节段缩短多少构成正常功能或不同程度的运动减弱。我们通过对在48小时内进行了放射性心室造影(RVG)的患者连续二维超声心动图研究进行回顾性分析,确定了将这些准则应用于公认的EF测定技术的准确性。使用12节段模型,我们根据节段偏移和增厚情况对心底和心室中部水平的每个节段进行评分。心尖部的评分方式类似,但基于圆柱 - 圆锥模型,其值为上述评分的1/3。EF由节段评分总和确定并进行视觉估计。我们将这种方法称为视觉定量估计(VQE)。我们将VQE得出的EF以及视觉估计得出的EF与RVG EF进行了相关性分析。在训练集中,VQE与RVG显示出很强的相关性(r = 0.969),显著高于视觉估计(r = 0.896,P < 0.01)。VQE的一致性界限(+12%至 -7%)与RVG与对比心室造影的一致性界限(+10%至 -11%)相似,观察者内和观察者间变异性也相似。在预测集中,VQE与RVG EF之间也观察到类似的相关性(r = 0.967,P < 0.001)。我们得出结论,VQE提供的EF估计值与RVG高度相关。