Gabarre Jean, Bossi Philippe
Services d'hématologie clinique et des maladies infectieuses et tropicales, hôpital Pitié-Salpêtrière, 47, boulevard de l'Hôpital, 75013 Paris.
Bull Cancer. 2003 May;90(5):419-25.
Highly active antiretroviral therapy (HAART) has changed the epidemiology of Kaposi's sarcoma (KS) and lymphoma occurring in people living with HIV. The KS's decrease was observed early after HAART availability: although delayed, the decrease of non Hodgkin lymphoma has been sign. The improvement of immune status due to HAART has decreased the occurrence of chemotherapy triggered opportunistic infections, and survival rates have been improved. The administration of chemotherapy with HAART does not seem to increase toxicity.
高效抗逆转录病毒疗法（HAART）改变了HIV感染者中卡波西肉瘤（KS）和淋巴瘤的流行病学情况。HAART可用后不久就观察到KS发病率下降：非霍奇金淋巴瘤的发病率虽有延迟，但也出现了下降。HAART带来的免疫状态改善减少了化疗引发的机会性感染的发生，生存率也得到了提高。HAART联合化疗似乎不会增加毒性。
