Yoo Kyung-Jong, Choi Donghoon, Choi Byoung Wook, Lim Sang-Hyun, Chang Byung-Chul
Department of Thoracic and Cardiovascular Surgery, Yonsei Cardiovascular Hospital, Yonsei University College of Medicine, Seoul, South Korea.
Eur J Cardiothorac Surg. 2003 Jul;24(1):86-91; discussion 91. doi: 10.1016/s1010-7940(03)00192-1.
Coronary angiography (CAG) is the gold standard method in evaluating graft patency following coronary artery bypass grafting (CABG), even though there are several kinds of non-invasive methods. Recently developed multi-slice CT (m-CT), having effective scan times up to 0.25 s and multi-row detector array systems, enable rapid imaging of cardiac structures, including coronary arteries during one breath-hold. We compared m-CT with CAG for the evaluation of graft patency following CABG.
Forty-two patients having undergone m-CT and CAG within 3 months of CABG were studied. Twenty-three patients underwent conventional CABG and 19 off-pump CABG. A total of 125 grafts were used, including 42 left internal mammary arteries (LIMA), 25 radial arteries (RA), 3 right internal mammary arteries (RIMA) and 55 vein grafts.
CAG showed a 96% (120/125) patency rate (1 LIMA, 2 RA and 2 vein grafts were occluded). m-CT showed a 98% (122/125) correct positive ratio with a sensitivity and specificity of 98 and 100%, respectively. The sensitivity in LIMA, RA, RIMA and vein grafts was 98, 91, 100 and 100%, respectively, with 100% specificity for all. There was an equivocal result in the competitive grafts with native coronary artery that were patent in the CAG, but faint opacification with no significant flow in the m-CT.
This study showed that m-CT was very simple, useful and accurate in evaluating graft patency during the early post-operative period following CABG, even though there was an equivocal result in the competitive grafts with a native coronary artery.
尽管有多种非侵入性方法,但冠状动脉造影(CAG)仍是评估冠状动脉旁路移植术(CABG)后移植血管通畅情况的金标准方法。最近开发的多层螺旋CT(m-CT),有效扫描时间可达0.25秒,并配备多排探测器阵列系统,能够在一次屏气过程中对包括冠状动脉在内的心脏结构进行快速成像。我们比较了m-CT与CAG在评估CABG后移植血管通畅情况方面的差异。
对42例在CABG后3个月内接受m-CT和CAG检查的患者进行研究。其中23例患者接受了传统CABG,19例接受了非体外循环CABG。共使用了125条移植血管,包括42条左乳内动脉(LIMA)、25条桡动脉(RA)、3条右乳内动脉(RIMA)和55条静脉移植血管。
CAG显示通畅率为96%(120/125)(1条LIMA、2条RA和2条静脉移植血管闭塞)。m-CT显示正确阳性率为98%(122/125),敏感性和特异性分别为98%和100%。LIMA、RA、RIMA和静脉移植血管的敏感性分别为98%、91%、100%和100%,所有血管的特异性均为100%。在与自身冠状动脉竞争的移植血管中,CAG显示通畅,但m-CT显示造影剂充盈模糊且无明显血流,结果不明确。
本研究表明,m-CT在评估CABG术后早期移植血管通畅情况方面非常简单、有用且准确,尽管在与自身冠状动脉竞争的移植血管中结果不明确。