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小儿患者节制排尿手术的结果:单机构经验

Outcome of continence procedures in the pediatric patient: a single institutional experience.

作者信息

Cole Emily E, Adams Mark C, Brock John W, Pope John C

机构信息

Division of Pediatric Urology, Vanderbilt University Medical Center, Nashville, Tennessee 37232-2765, USA.

出版信息

J Urol. 2003 Aug;170(2 Pt 1):560-3; discussion 563. doi: 10.1097/01.ju.0000078015.55801.52.

Abstract

PURPOSE

Achieving continence remains a major goal in the treatment of children with neurogenic and/or anatomical voiding dysfunction. We reviewed our experience with continence procedures in pediatric lower urinary tract reconstruction.

MATERIALS AND METHODS

We reviewed the records of all pediatric patients who underwent continence procedures at our institution since July 1993. We reviewed the diagnosis, type of primary reconstructive procedure, concomitant procedure(s) and initial success rate. In cases of primary failure we noted the type of secondary continence procedure performed and the ultimate success rate. Success was defined as dry intervals of at least 4 hours when the patient was compliant with a catheterization or voiding regimen.

RESULTS

Primary continence procedures were performed in 43 cases and secondary procedures were performed in 6 for a total of 49 continence procedures. The diagnoses included myelomeningocele in 22 patients, exstrophy in 12, epispadias in 3, bilateral single system ureteral ectopia in 3 and spinal cord injury in 3. A total of 32 primary procedures were performed concomitantly with or were preceded by bladder augmentation with creation of a catheterizable stoma. The remaining 11 patients underwent a continence procedure only. The diagnosis in these 11 patients was exstrophy in 5, epispadias in 3, with spinal cord injury in 2 and myelomingocele in 1. Mean followup was 35 months (range 1 to 95). Initial continence procedures included Young-Dees-Leadbetter bladder neck repair in 14 cases, of which 11 (79%) were initially successful, a urethral sling in 9 with 7 initial successes (78%), bladder neck division and closure in 7 with all successful (100%), collagen in 5 with 1 success (20%), other urethral lengthening procedure (eg Pippi Salle or Kropp) in 4 with 3 successes, (75%), combined urethral sling and Young-Dees-Leadbetter in 2 with 1 success (50%), and an artificial sphincter and fascial wrap in 1 each, which were successful. Of the 6 secondary procedures performed for primary failure collagen was injected in 4 and the bladder neck was divided and closed in 2. All were successful.

CONCLUSIONS

Various lower urinary tract procedures can be performed to achieve successful continence in the pediatric population. At our institution all procedures had a reasonable success rate except primary collagen injection. Collagen injection and bladder neck division/closure proved to be reliable secondary procedures in cases of primary failure.

摘要

目的

实现控尿仍然是神经源性和/或解剖性排尿功能障碍患儿治疗的主要目标。我们回顾了我们在小儿下尿路重建中进行控尿手术的经验。

材料与方法

我们回顾了自1993年7月以来在本机构接受控尿手术的所有儿科患者的记录。我们回顾了诊断、初次重建手术类型、伴随手术及初始成功率。对于初次手术失败的病例,我们记录了二次控尿手术的类型及最终成功率。成功定义为患者依从导尿或排尿方案时至少4小时的干爽间隔。

结果

共进行了43例初次控尿手术和6例二次手术,总计49例控尿手术。诊断包括脊髓脊膜膨出22例、膀胱外翻12例、尿道上裂3例、双侧单系统输尿管异位3例和脊髓损伤3例。总共32例初次手术与膀胱扩大术同时进行或在膀胱扩大术之前进行,并建立了可导尿的造口。其余11例患者仅接受了控尿手术。这11例患者的诊断为膀胱外翻5例、尿道上裂3例、脊髓损伤2例和脊髓脊膜膨出1例。平均随访35个月(范围1至95个月)。初次控尿手术包括14例Young-Dees-Leadbetter膀胱颈修复术,其中11例(79%)初次成功;9例尿道悬带术,7例初次成功(78%);7例膀胱颈切开并缝合术,全部成功(100%);5例胶原蛋白注射,1例成功(20%);4例其他尿道延长手术(如Pippi Salle或Kropp手术),3例成功(75%);2例联合尿道悬带术和Young-Dees-Leadbetter手术,1例成功(50%);人工括约肌和筋膜包裹术各1例,均成功。在为初次手术失败而进行的6例二次手术中,4例注射了胶原蛋白,2例进行了膀胱颈切开并缝合术。全部成功。

结论

可以进行各种下尿路手术以在儿科患者中成功实现控尿。在我们机构,除了初次胶原蛋白注射外,所有手术都有合理的成功率。胶原蛋白注射和膀胱颈切开/缝合术在初次手术失败的情况下被证明是可靠的二次手术。

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