Vallancien G, Chopin D, Davila C, Guiillonneau B, Perreira E, Veillon B, Brisset J M, Andre-Bougaran J
Centre Médico-Chirurgical de la Porte de Choisy, Département d'Urologie, Paris.
Prog Urol. 1991 Feb;1(1):149-53.
The objective of this study was to develop an apparatus allowing the generation of a high temperature (exceeding 80 degrees C) in a precise focus (20 mm x 2 mm) by means of extracorporeal elastic waves. The treatment time at high temperatures is brief and administered in sequences of 4 to 7 seconds. In vitro studies on blocks of polyurethane demonstrated melting of the plastic at the focal point. Studies on plastic spheres introduced into the bladder of the pig demonstrated melting of the sphere without any alteration in the tissues in the wave path. Studies of cellular viability of bladder carcinoma cultures demonstrated a significant difference after 48 hours between the non-treated control group and the group of cells submitted to high temperatures. This technique, called Pyrotherapy, should be promising if the preliminary results are confirmed.
本研究的目的是开发一种装置，该装置能够通过体外弹性波在精确焦点（20毫米×2毫米）产生高温（超过80摄氏度）。高温治疗时间短暂，以4至7秒的序列进行给药。对聚氨酯块的体外研究表明，焦点处的塑料发生了熔化。对引入猪膀胱的塑料球的研究表明，球体发生了熔化，而波传播路径中的组织没有任何改变。对膀胱癌细胞培养物的细胞活力研究表明，在48小时后，未处理的对照组与接受高温处理的细胞组之间存在显著差异。如果初步结果得到证实，这种称为热疗法的技术应该很有前景。
