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聚焦体外热疗。

Focused extracorporeal pyrotherapy.

作者信息

Vallancien G, Chartier-Kastler E, Bataille N, Chopin D, Harouni M, Bougaran J

机构信息

Department of Urology, CMC de la Porte de Choisy, Paris, France.

出版信息

Eur Urol. 1993;23 Suppl 1:48-52. doi: 10.1159/000474680.

DOI:10.1159/000474680
PMID:7685697
Abstract

A system generating focused elastic ultrashort waves has been developed with the aim to destroy tumors by an extracorporeal way. Experimental studies on different targets (plastic phantoms, organ samples and normal live tissues in pigs) have been done showing the good focusing of the device and the possibility of getting a focal tissular coagulative necrosis. Studies on cultured tumor cells and implanted tumors in rats have shown a local effect on cells or tumor growth with the absence of metastatic risks. First human trials are summarized. This technique we call focused extracorporeal pyrotherapy could be useful for the treatment of cancers.

摘要

一种产生聚焦弹性超短波的系统已被开发出来,目的是以体外方式破坏肿瘤。已针对不同目标(塑料模型、器官样本和猪的正常活体组织)开展了实验研究,结果表明该设备具有良好的聚焦效果,并有可能实现局部组织凝固性坏死。对培养的肿瘤细胞和大鼠体内植入肿瘤的研究表明,该技术对细胞或肿瘤生长有局部作用,且不存在转移风险。文中总结了首次人体试验情况。我们将这种技术称为聚焦体外热疗,它可能对癌症治疗有用。

相似文献

1
Focused extracorporeal pyrotherapy.聚焦体外热疗。
Eur Urol. 1993;23 Suppl 1:48-52. doi: 10.1159/000474680.
2
Focused extracorporeal pyrotherapy: experimental study and feasibility in man.聚焦体外热疗:人体实验研究及可行性
Semin Urol. 1993 Feb;11(1):7-9.
3
Focussed extracorporeal pyrotherapy: experimental results.聚焦体外热疗:实验结果
Eur Urol. 1991;20(3):211-9. doi: 10.1159/000471702.
4
[Focused extracorporeal pyrotherapy. Initial experimental results].[聚焦体外热疗。初步实验结果]
Prog Urol. 1991 Feb;1(1):149-53.
5
Ablation of superficial bladder tumors with focused extracorporeal pyrotherapy.聚焦体外热疗消融浅表膀胱肿瘤。
Urology. 1996 Feb;47(2):204-7. doi: 10.1016/S0090-4295(99)80417-8.
6
The effects of focused extracorporeal pyrotherapy on a human bladder tumor cell line (647 V).
J Urol. 1993 Mar;149(3):643-7. doi: 10.1016/s0022-5347(17)36171-2.
7
Antitumoral local effect and metastatic risk of focused extracorporeal pyrotherapy on Dunning R-3327 tumors.聚焦体外热疗对Dunning R-3327肿瘤的抗肿瘤局部效应及转移风险
Eur Urol. 1996;29(1):72-7. doi: 10.1159/000473722.
8
High-energy shock waves pyrotherapy. A new concept in extracorporeal tumour therapy.
Surg Oncol. 1993;2(3):197-203. doi: 10.1016/0960-7404(93)90007-l.
9
Tissue ablation in benign prostatic hyperplasia with high-intensity focused ultrasound.高强度聚焦超声用于良性前列腺增生的组织消融
Eur Urol. 1993;23 Suppl 1:39-43. doi: 10.1159/000474678.
10
High intensity focused ultrasound in benign prostatic hyperplasia.高强度聚焦超声治疗良性前列腺增生症
Eur J Ultrasound. 1999 Mar;9(1):55-60. doi: 10.1016/s0929-8266(99)00012-9.

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2
Short-duration-focused ultrasound stimulation of Hsp70 expression in vivo.体内短期聚焦超声刺激Hsp70表达。
Phys Med Biol. 2008 Jul 7;53(13):3641-60. doi: 10.1088/0031-9155/53/13/017. Epub 2008 Jun 19.
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Use of a microbubble agent to increase the effects of high intensity focused ultrasound on liver tissue.使用微泡剂增强高强度聚焦超声对肝脏组织的作用。
Eur Radiol. 2005 Jul;15(7):1415-20. doi: 10.1007/s00330-005-2663-7. Epub 2005 Mar 1.
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Update on minimally invasive approaches to kidney tumors.肾肿瘤微创治疗方法的最新进展
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Ceramic coagulation tip for interstitial thermoablation of the prostate: first experiments.用于前列腺间质热消融的陶瓷凝固尖端:首次实验
Int Urol Nephrol. 1998;30(2):145-51. doi: 10.1007/BF02550569.