Kawasaki Shiro, Uno Toshihiko, Shimamura Ichiro, Ohashi Yuichi
Department of Ophthalmology, Ehime University School of Medicine, Shitsukawa, Shigenobu-cho, Onsen-gun, Ehime 791-0295, Japan.
Nippon Ganka Gakkai Zasshi. 2003 Jun;107(6):316-21.
Preserved human amniotic membrane has been used in reconstruction of the ocular surface. In this paper, we report our method of amniotic membrane transplantation (AMT) for recurrent pterygium.
Twenty-six eyes of 26 patients with recurrent pterygium are reported. All subjects were operated on with an extensive excision of the subconjunctival fibrous tissues followed by application of mitomycin C (0.04%, 3-5 min) during the operation. Amniotic membrane transplantation was performed with implantation of conjunctival autograft in cases with a large excision.
The mean follow up time was 17.3 +/- 9.3 (mean +/- standard deviation) months. Twelve eyes showed severe symblepharon and 14 patients suffered from double vision before the operation. There were only three mild recurrences (12%), 11 patients recovered from double vision, and no major complications such as sclermalasia were noted during the follow-up period.
AMT with application of mitomycin C is effective in preventing pterygium recurrence and for improved ocular movement. The cosmetic outcome of our methods has also been satisfactory.
保存的人羊膜已用于眼表重建。在本文中，我们报告了我们用于复发性翼状胬肉的羊膜移植（AMT）方法。
报告了26例复发性翼状胬肉患者的26只眼。所有患者均接受手术，广泛切除结膜下纤维组织，术中应用丝裂霉素C（0.04%，3 - 5分钟）。对于切除范围较大的病例，在羊膜移植的同时植入结膜自体移植片。
平均随访时间为17.3±9.3（平均值±标准差）个月。术前12只眼有严重睑球粘连，14例患者有复视。随访期间仅3例轻度复发（12%），11例患者复视恢复，未发现巩膜软化等严重并发症。
应用丝裂霉素C的羊膜移植在预防翼状胬肉复发和改善眼球运动方面有效。我们方法的美容效果也令人满意。
