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Mitomycin C and conjunctival autograft for recurrent pterygium.

作者信息

Altiparmak Uğur E, Katircioğlu Yasemin Aslan, Yağci Ramazan, Yalniz Züleyha, Duman Sunay

机构信息

Department of Ophthalmology, Ankara Training and Research Hospital, Ankara, Turkey.

出版信息

Int Ophthalmol. 2007 Dec;27(6):339-43. doi: 10.1007/s10792-007-9085-2. Epub 2007 May 8.

DOI:10.1007/s10792-007-9085-2
PMID:17486295
Abstract

PURPOSE

To observe the efficiency of intraoperative low-dose Mitomycin-C combined with conjunctival autograft in the treatment of recurrent pterygium.

METHODS

Fifteen eyes with recurrent pterygium were included in this study. The mean age of the patients was 51.6 +/- 11.4 (9 men, 6 women). All patients underwent excision of the pterygium tissue and subconjunctival fibrous tissue with a no cautery approach. 0.2 mg/ml Mitomycin-C (0.02%) was applied for 3 min. Conjunctival autograft was obtained from the superotemporal bulbar conjunctiva of the same eye. Eyes were followed for a mean period of 21.0 +/- 9.1 months.

RESULTS

Recurrence was seen in two eyes (13.3%) during the follow-up period. The only complication seen was graft edema (two eyes; 13.3%) which healed after pressure patching. Graft necrosis, scleral melting or failure of revascularization was not noted.

CONCLUSION

Intraoperative application of 0.2 mg/ml Mitomycin-C combined with conjunctival autograft reduces recurrence in recurrent pterygium cases, with minimal complications.

摘要

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Evaluation of limbal conjunctival autograft and low-dose mitomycin C in the treatment of recurrent pterygium.自体角膜缘结膜移植联合低剂量丝裂霉素C治疗复发性翼状胬肉的疗效评估
Ophthalmic Surg Lasers Imaging. 2003 May-Jun;34(3):193-6.
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Subconjunctival mitomycin C as adjunctive therapy before pterygium excision.翼状胬肉切除术前结膜下注射丝裂霉素C作为辅助治疗。
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