Santaló Bel Miguel, Guindo Soldevila Josep, Ordóñez Llanos Jordi
Complejo de Urgencias, Emergencias y Críticos. Hospital de la Santa Creu i Sant Pau. Universidad Autónoma. Barcelona. España.
Rev Esp Cardiol. 2003 Jul;56(7):703-20. doi: 10.1016/s0300-8932(03)76942-5.
New biological markers of myocardial injury have improved the management of patients with acute coronary syndromes. Among these markers, the most relevant are the cardiac troponins (troponin I and troponin T) because of their cardiospecificity, and myoglobin because of its combination of diagnostic sensitivity and usefulness for an early diagnosis. The serial analysis and combined use of both markers fulfill all diagnostic and prognostic requirements, and are helpful in indicating therapeutic strategies for acute coronary syndromes. However, these markers also have limitations, and their concentrations should always be interpreted in the light of the patient's clinical status.
心肌损伤的新生物标志物改善了急性冠状动脉综合征患者的管理。在这些标志物中,最相关的是心肌肌钙蛋白(肌钙蛋白I和肌钙蛋白T),因其具有心脏特异性,还有肌红蛋白,因其兼具诊断敏感性和早期诊断的实用性。这两种标志物的系列分析和联合使用满足了所有诊断和预后要求,并有助于指明急性冠状动脉综合征的治疗策略。然而,这些标志物也有局限性,其浓度应始终根据患者的临床状况进行解读。