Jerusalem G, Hustinx R, Beguin Y, Fillet G
Department of Medicine, Division of Medical Oncology and Hematology, CHU Sart Tilman, B35, B-4000-Liege 1, Belgium.
Eur J Cancer. 2003 Jul;39(11):1525-34. doi: 10.1016/s0959-8049(03)00374-5.
With the emergence of positron emission tomography (PET) from research laboratories into routine clinical use, it is important to redefine the most appropriate use of each imaging technique. The aim of this review article is to show the potential of PET in oncology. We discuss the most promising indications and the perspectives for the future. We will also point out the shortcomings and the important questions to be answered before fully considering PET as a necessary tool in the day-to-day practice of oncology. Although many studies have documented the high accuracy of 18F-FDG PET for the detection and staging of malignant tumours and for the monitoring of therapy results in these patients, it is very important to assess the impact of the technique on patient outcome and to show cost-effectiveness from the societal viewpoint.
随着正电子发射断层扫描(PET)从研究实验室进入常规临床应用,重新定义每种成像技术的最恰当用途变得很重要。这篇综述文章的目的是展示PET在肿瘤学中的潜力。我们讨论了最有前景的适应症以及未来的前景。我们还将指出其缺点以及在将PET完全视为肿瘤学日常实践中的必要工具之前需要回答的重要问题。尽管许多研究已证明18F-FDG PET在检测和分期恶性肿瘤以及监测这些患者的治疗结果方面具有很高的准确性,但从社会角度评估该技术对患者预后的影响并证明其成本效益非常重要。