Morata Thais C
Hearing Loss Prevention Section, Division of Applied Research and Technology, National Institute for Occupational Safety and Health/C27, 4676 Columbia Parkway, Cincinnati, OH 45226, USA.
J Occup Environ Med. 2003 Jul;45(7):676-82. doi: 10.1097/01.jom.0000071507.96740.70.
In 2002, the National Institute for Occupational Safety and Health and the National Hearing Conservation Association cosponsored the "Best Practices Workshop: Combined Effects of Chemicals and Noise on Hearing." This article summarizes the main results of the Workshop. Its goals were to review the knowledge of chemical ototoxicity and to stimulate participant discussion on how to address this risk. Speakers provided an overview of the effects of chemicals on the auditory system (http://www.cdc.gov/niosh/noise/noiseandchem/noiseandchem.html). Research priorities were discussed in concurrent working group sessions. The Workshop concluded with a panel of the groups' facilitators reporting on these sessions. The following key issues were identified: rationale and proposal of a list of priority chemicals; valid procedures for exposure (animal studies), exposure assessment, and audiological testing; need for mechanistic research and a Response Level; recommendations for preventive actions; and information dissemination.
2002年，美国国家职业安全与健康研究所和国家听力保护协会共同主办了“最佳实践研讨会：化学品与噪声对听力的联合影响”。本文总结了该研讨会的主要成果。其目标是回顾化学性耳毒性方面的知识，并激发参与者就如何应对这一风险展开讨论。发言者概述了化学品对听觉系统的影响（http://www.cdc.gov/niosh/noise/noiseandchem/noiseandchem.html）。在同期的工作组会议上讨论了研究重点。研讨会最后由各小组的主持人组成的小组汇报这些会议的情况。确定了以下关键问题：优先化学品清单的基本原理和提议；有效的暴露程序（动物研究）、暴露评估和听力测试；对机理研究和反应水平的需求；预防行动建议；以及信息传播。
