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工作场所耳毒性的管理方法。

Approaches to managing ototoxicity in the workplace.

作者信息

Morata Thais C, Carlson Krystin, Fuente Adrian, Poling Gayla L, Garinis Angela, Hullar Timothy, Lee John, Pouyatos Benoit, Sliwinska-Kowalska Mariola, Dreisbach Laura, Stuehm Hunter, Konrad-Martin Dawn

机构信息

Division of Field Studies and Engineering, National Institute for Occupational Safety and Health, Cincinnati, OH, USA.

Faculté de Médecine, Université de Montréal, Montréal, Québec, Canada.

出版信息

Int J Audiol. 2025 Jun 14:1-10. doi: 10.1080/14992027.2025.2508728.

DOI:10.1080/14992027.2025.2508728
PMID:40516095
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12302989/
Abstract

OBJECTIVE

Ototoxic chemicals in the workplace can pose a risk to hearing and balance functions. Our objective was to identify evidence-based practices for occupational health settings in managing ototoxicity. This resulted in the document, created by the International Ototoxicity Management Group.

DESIGN

To develop a practical approach for any workplace, we reviewed a variety of sources and used an international panel of interdisciplinary experts. Evidence included data from experimental, observational, and review studies. Thirty-two subject matter experts were invited to review the document; twenty-two completed the review and unanimously endorsed the ototoxicity management system as proposed.

RESULTS

Six key action steps were proposed to: (1) identify workers exposed to ototoxic chemicals, (2) perform auditory and vestibular assessments, (3) follow-up after monitoring health, (4) document worker data, (5) maintain healthy safety culture, and (6) review ototoxicity management approach. These steps focus on the management of workers who are at-risk for workplace ototoxic chemical exposure at any level (with or without concurrent noise exposures).

CONCLUSIONS

Early identification strategies include self-report questionnaires; auditory testing; vestibular screening; referrals for diagnosis; management of cases; and monitoring of exposure scenarios to prevent further cases.

摘要

目的

工作场所中的耳毒性化学物质会对听力和平衡功能构成风险。我们的目标是确定职业健康环境中管理耳毒性的循证实践方法。这促成了由国际耳毒性管理小组编制的这份文件。

设计

为了为任何工作场所制定一种实用方法,我们查阅了各种资料来源,并组建了一个跨学科国际专家小组。证据包括来自实验性、观察性和综述性研究的数据。邀请了32位主题专家审阅该文件;22位完成了审阅并一致认可所提议的耳毒性管理系统。

结果

提出了六个关键行动步骤,以:(1)识别接触耳毒性化学物质的工人,(2)进行听觉和前庭评估,(3)在监测健康状况后进行随访,(4)记录工人数据,(5)维持健康的安全文化,以及(6)审查耳毒性管理方法。这些步骤侧重于管理在任何水平上有工作场所耳毒性化学物质接触风险的工人(无论是否同时接触噪声)。

结论

早期识别策略包括自我报告问卷;听觉测试;前庭筛查;诊断转诊;病例管理;以及监测接触情况以预防更多病例。

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本文引用的文献

1
Prevalence of Ototoxic Chemical Exposure, Noise Exposure and Hearing Difficulty Among Workers in the United States, 2023.2023年美国工人中耳毒性化学物质暴露、噪声暴露及听力困难的患病率
J Occup Environ Med. 2025 May 8. doi: 10.1097/JOM.0000000000003445.
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Which Environmental Pollutants Are Toxic to Our Ears?-Evidence of the Ototoxicity of Common Substances.哪些环境污染物对我们的耳朵有毒?——常见物质耳毒性的证据。
Toxics. 2024 Sep 4;12(9):650. doi: 10.3390/toxics12090650.
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The effect of occupational exposure to noise and chemical agents on hearing abilities.职业性噪声和化学因素暴露对听觉能力的影响。
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Lancet Glob Health. 2024 Feb;12(2):e217-e225. doi: 10.1016/S2214-109X(23)00514-4.
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Increasing Hearing Readiness Using Boothless Audiometry.使用无耳罩测听法提高听力准备度。
Mil Med. 2023 Nov 8;188(Suppl 6):529-535. doi: 10.1093/milmed/usad224.
6
Audiological Tests Used in the Evaluation of the Effects of Solvents on the Human Auditory System: A Mixed Methods Review.用于评估溶剂对人体听觉系统影响的听力学测试:一项混合方法综述
Semin Hear. 2023 Jul 21;44(4):437-469. doi: 10.1055/s-0043-1769585. eCollection 2023 Nov.
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Evaluating the potential impact of ototoxicant exposure on worker health.评估耳毒性物质暴露对工人健康的潜在影响。
J Occup Environ Hyg. 2023 Nov;20(11):520-535. doi: 10.1080/15459624.2023.2240874. Epub 2023 Sep 5.
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Is jet fuel exposure associated with central auditory nervous system difficulties: An exploratory study in military personnel.喷气燃料暴露与中枢听觉神经系统困难有关吗:军事人员的探索性研究。
J Acoust Soc Am. 2022 Mar;151(3):2027. doi: 10.1121/10.0009845.
9
Pure Tone Audiometry Evaluation Method Effectiveness in Detecting Hearing Changes Due to Workplace Ototoxicant, Continuous Noise, and Impulse Noise Exposures.纯音测听评估方法在检测因工作场所耳毒性、连续噪声和脉冲噪声暴露引起的听力变化方面的有效性。
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10
Effect of noise and ototoxicants on developing standard threshold shifts at a U.S. Air Force depot level maintenance facility.美国空军仓库级维修设施中噪声和耳毒性药物对发育中标准阈值偏移的影响。
J Occup Environ Hyg. 2021 Jul;18(7):323-333. doi: 10.1080/15459624.2021.1922693. Epub 2021 Jun 8.