Hill M P, Balme B, Gho A, Perrot H
Service de Dermatologie, Hôpital de l'Hôtel-Dieu, Lyon.
Ann Dermatol Venereol. 1992;119(9):651-4.
A case of non-actinic disseminated superficial porokeratosis with dermal amyloid deposits in a 53 year-old-man is reported. The lesions of the trunk and arms were typical, but annular lesions of the ankles were lichenoid. The amyloid deposits were present under the cornoid lamella in the typical lesions and absent in the annular lesions. The different clinical variants of porokeratosis are discussed. The origin of amyloidosis is debated; it seems to be epidermic, due to degeneration of the keratinocytes. The secondary cutaneous amyloidosis is usually described in association with epithelial tumors or psoriasis, but exceptionally with porokeratosis.
报告了一例53岁男性患非光化性播散性浅表性汗孔角化症并伴有真皮淀粉样沉积的病例。躯干和手臂的皮损典型,但脚踝部的环形皮损呈苔藓样。淀粉样沉积存在于典型皮损的角质形成板下方,而环形皮损中则不存在。文中讨论了汗孔角化症的不同临床变型。淀粉样变性的起源存在争议;似乎是表皮性的,由角质形成细胞变性所致。继发性皮肤淀粉样变性通常与上皮肿瘤或银屑病相关,但罕见与汗孔角化症相关。