Paul C, Janier M, Carlet J, Tamion F, Carlotti A, Fichelle J M, Daniel F
Service de Dermatologie, Hôpital Saint-Joseph, Paris.
Ann Dermatol Venereol. 1992;119(9):667-9.
We report the case of a 38-year old man who developed erythroderma during treatment with teicoplanin for staphylococcal septicaemia. The clinical symptoms, which included high fever, shock and erythroderma, were suggestive of staphylococcal toxic shock. After teicoplanin was withdrawn and replaced by vancomycin the disease followed a favourable course. The reintroduction test was positive. This case illustrates the problems associated with the diagnosis of erythroderma in intensive care patients and confirms that it is possible to prescribe vancomycin in cases with allergic reaction to teicoplanin.
我们报告了一例38岁男性患者，其在接受替考拉宁治疗葡萄球菌败血症期间出现了红皮病。临床症状包括高热、休克和红皮病，提示为葡萄球菌性中毒性休克。停用替考拉宁并换用万古霉素后，病情呈好转趋势。再激发试验呈阳性。该病例说明了重症监护患者红皮病诊断中存在的问题，并证实了在对替考拉宁过敏的病例中可以使用万古霉素。
