Gidaiatov A A, Alieva S A
Klin Med (Mosk). 2003;81(5):40-3.
Endoscopic and morphological examinations of the upper gastrointestinal tract (GIT) were made in 80 patients with nonspecific ulcerative colitis (NUC). Tests for Helicobacter pylori infection and gastric juice acidity were also conducted. It was found that in many patients NUC was associated with development of nonspecific esophagitis, gastritis and duodenitis. The endoscopic examination revealed erosions of the abdominal esophagus in 13.8% cases, erosive-ulcerative alterations in the stomach and duodenum in 27.5% of NUC patients. The most marked changes occurred in patients with severe NUC. Alterations in the upper GIT were not related with either Hp or the acidity. Morphological examinations of the biopsies from the esophagus, stomach and duodenum demonstrated changes similar to those in biopsy material from the colon. The same type of morphological changes in mucosa from the upper GIT and the colon in NUC indicates that their pathogenesis is also the same.
对80例非特异性溃疡性结肠炎（NUC）患者进行了上消化道（GIT）的内镜和形态学检查。还进行了幽门螺杆菌感染检测和胃液酸度检测。结果发现，许多NUC患者伴有非特异性食管炎、胃炎和十二指肠炎症。内镜检查显示，13.8%的病例存在腹段食管糜烂，27.5%的NUC患者胃和十二指肠有糜烂性溃疡改变。最明显的变化发生在重度NUC患者中。上消化道的改变与幽门螺杆菌或酸度均无关。对食管、胃和十二指肠活检组织的形态学检查显示，其变化与结肠活检材料相似。NUC患者上消化道和结肠黏膜的形态学改变类型相同，表明其发病机制也相同。
