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[普贝生用于因医学指征引产时宫颈条件不佳促成熟效果的研究]

[Study of the effect of Propess for ripening of the unfavorable cervix for the induction of labor due to medical indications].

作者信息

Nikolov A, Dimitrov A, Krŭsteva K, Nashar S

出版信息

Akush Ginekol (Sofiia). 2003;42(3):5-8.

PMID:12858482
Abstract

The purpose of this study is to proceed and estimate the effect of Propess for cervical ripening for induction of labor due to medical indications. Seventy pregnant women are included divided in two groups-36 of them with vaginally applicated Propess and the other 34 are at the control group. Changes in the cervix, induction of uterine activity, labor, status of the fetus and the side effects are proceeded. In the group with vaginally applicated Propess 9 of the patients gave birth till the twelfth hour from the application of the pessar. The Bishop score increased over 6 points in 7 of them and increased by 3 points in 11 of the cases within 12 hours. In the control group no delivery is registered till the twelfth hour, in two of the cases there is an increase of the Bishop score over 6 points and only in 5 of the cases is estimated an increase of the Bishop score with 3 points. There is one case of uterine hyperstimulation. There was no other side effects.

摘要

本研究的目的是进行并评估普贝生用于因医学指征引产时促宫颈成熟的效果。纳入70名孕妇,分为两组,其中36名经阴道使用普贝生,另外34名作为对照组。观察宫颈变化、子宫活动诱导情况、分娩情况、胎儿状况及副作用。在经阴道使用普贝生的组中,9名患者在放置 pessar 后12小时内分娩。其中7名患者的 Bishop 评分在12小时内增加超过6分,11名患者增加3分。对照组在12小时内无分娩记录,2例患者的 Bishop 评分增加超过6分,仅有5例患者的 Bishop 评分估计增加3分。有1例子宫过度刺激情况。无其他副作用。

相似文献

1
[Study of the effect of Propess for ripening of the unfavorable cervix for the induction of labor due to medical indications].[普贝生用于因医学指征引产时宫颈条件不佳促成熟效果的研究]
Akush Ginekol (Sofiia). 2003;42(3):5-8.
2
The influence of dinoprostone on uterine cervix ripening and the course of labor.地诺前列酮对子宫颈成熟及产程的影响。
Neuro Endocrinol Lett. 2007 Aug;28(4):513-7.
3
[Clinical evaluation of propess for induction of term pregnancy].[普贝生用于足月妊娠引产的临床评估]
Zhonghua Fu Chan Ke Za Zhi. 2003 Apr;38(4):210-2.
4
[Dinoprostone: slow release vaginal insert (Propess) and intracervical gel (Prepidil) for the induction of labour with unriped cervix].地诺前列酮:用于未成熟宫颈引产的缓释阴道栓剂(普贝生)和宫颈内凝胶(普贝生)
Minerva Ginecol. 2004 Oct;56(5):413-8.
5
[Pharmacological induction of labour: benefits and risks].[药物引产:益处与风险]
Minerva Ginecol. 2007 Aug;59(4):347-55.
6
[Uterine hyperstimulation following cervix ripening with dinoprostone in a vaginal insert system].[阴道栓剂系统中使用地诺前列酮进行宫颈成熟后出现子宫过度刺激]
Ned Tijdschr Geneeskd. 2004 Jun 26;148(26):1300-3.
7
Elective cervical ripening in women beyond the 290th day of pregnancy: a randomized trial comparing 2 dinoprostone preparations.妊娠290天以上女性的择期宫颈成熟:比较两种地诺前列酮制剂的随机试验
J Reprod Med. 2007 Oct;52(10):945-9.
8
A randomized controlled trial of 24-hour vaginal dinoprostone pessary compared to gel for induction of labor in term pregnancies with a Bishop score < or = 4.一项 24 小时阴道用前列腺素 E2 栓与凝胶用于 Bishop 评分≤4 的足月妊娠引产的随机对照试验。
Acta Obstet Gynecol Scand. 2010 May;89(5):651-7. doi: 10.3109/00016340903575998.
9
[Uterine hyperstimulation following cervix ripening with dinoprostone in a vaginal insert system].
Ned Tijdschr Geneeskd. 2005 Jan 8;149(2):105-6; author reply 106.
10
Efficacy and safety of six hourly vaginal misoprostol versus intracervical dinoprostone: a randomized controlled trial.每六小时阴道用米索前列醇与宫颈内用地诺前列酮的疗效及安全性:一项随机对照试验
Arch Gynecol Obstet. 2007 Aug;276(2):119-24. doi: 10.1007/s00404-006-0313-1.

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Vaginal prostaglandin (PGE2 and PGF2a) for induction of labour at term.足月引产用阴道前列腺素(前列腺素E2和前列腺素F2α)
Cochrane Database Syst Rev. 2014 Jun 19;2014(6):CD003101. doi: 10.1002/14651858.CD003101.pub3.