Hocevar A, Tomsic M, Praprotnik S, Hojnik M, Kveder T, Rozman B
Department of Rheumatology, Medical Centre Ljubljana, SI 1000 Ljubljana, Slovenia.
Ann Rheum Dis. 2003 Aug;62(8):702-4. doi: 10.1136/ard.62.8.702.
In the past sicca syndromes were attributed to destruction of glandular tissue. It is now thought that cytokines, autoantibodies, and parasympathetic nervous system dysfunction all have an important role in the xerostomia and xerophthalmia in Sjögren's syndrome.
过去,干燥综合征被认为是腺组织破坏所致。现在认为,细胞因子、自身抗体和副交感神经系统功能障碍在干燥综合征的口干和眼干中均起重要作用。