[牛奶中类雌激素产品对前列腺和睾丸的影响]
[The effects of estrogen-like products in milk on prostate and testes].
作者信息
Li Xiang-Ming, Ganmaa Davaasambuu, Qin Li-Qiang, Liu Xiu-Fan, Sato Akio
机构信息
Key Laboratory of Animal Infectious Diseases of Ministry of Agriculture, Yangzhou University, Yangzhou, Jiangsu 225001, China.
出版信息
Zhonghua Nan Ke Xue. 2003 Jun;9(3):186-90.
OBJECTIVES
To study the effects of estrogen-like products in milk on the male reproductive system.
METHODS
The incidence rates of testicular and prostatic cancers in 42 countries (regions), collected from the cancer incidence in five continent database (1988-1992), were correlated with the relative food consumption in these countries, which was provided by FAO database (1961-1990); two-generation reproduction test was taken by using Wistar rats according to FDA standard.
RESULTS
Among the food items examined, milk was most closely correlated (r = 0.711) with prostatic cancer incidence, followed by meat and coffee. As for testicular cancer, cheese was most closely correlated (r = 0.804) with the incidences in ages of 20-39, followed by animal fat and milk. No significant decreases of reproductive organ weight were found after the rats had been fed a lot of milk for long time.
CONCLUSIONS
The results suggest that further studies should be taken on the effects of estrogen-like products in milk on the male reproductive health.
目的
研究牛奶中类雌激素物质对雄性生殖系统的影响。
方法
从五大洲癌症发病率数据库（1988 - 1992年）收集42个国家（地区）睾丸癌和前列腺癌的发病率，并与粮农组织数据库（1961 - 1990年）提供的这些国家的相对食物消费量相关联；按照美国食品药品监督管理局标准，用Wistar大鼠进行两代繁殖试验。
结果
在所检测的食物中，牛奶与前列腺癌发病率的相关性最高（r = 0.711），其次是肉类和咖啡。对于睾丸癌，奶酪与20 - 39岁年龄段的发病率相关性最高（r = 0.804），其次是动物脂肪和牛奶。大鼠长期大量饮用牛奶后，生殖器官重量未发现显著下降。
结论
结果表明，应进一步研究牛奶中类雌激素物质对男性生殖健康的影响。
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