Speroff L
J Reprod Med. 1975 Nov;15(5):181-8.
This review asserts that prostaglandins of the E family play a vital regulatory role in uteroplacental blood flow. This role appears to be similar to activity within other organs, especially the kidney, in a process referred to as autoregulation of blood flow. This mechanism may serve as a system for ehmodynamic homeostasis in pregnancy. Moreover, hypertension in pregnancy (toxemia) may be due to a specific or generalized abnormality in this system.
本综述认为,E 族前列腺素在子宫胎盘血流中起着至关重要的调节作用。这一作用似乎与其他器官(尤其是肾脏)内的活动相似,这一过程被称为血流的自动调节。这种机制可能是孕期血流动力学稳态的一个系统。此外,妊娠期高血压(毒血症)可能是由于该系统中的特定或普遍异常所致。